使用单光子吸收法测量手部骨矿物质含量。

Measurement of hand bone mineral content using single-photon absorptiometry.

作者信息

Nicoll J J, Smith M A, Reid D, Law E, Brown N, Tothill P, Nuki G

出版信息

Phys Med Biol. 1987 Jun;32(6):697-706. doi: 10.1088/0031-9155/32/6/003.

Abstract

A single photon absorption imaging technique has been developed to assess the bone mass of the hand, especially in patients with rheumatoid arthritis or bronchial asthma. A modified rectilinear scanner images the hand by transmission scanning in a water bath with a 7.4 GBq 125I source. A microcomputer is used to calculate the bone mineral distribution, and the total bone mineral content (BMC) of the hand is determined from that distribution. The precision (coefficient of variation) of the measurement is 1.9%. A control population of 20 men and 58 women has been studied to determine normal variations in hand bone mineral content with age, sex, body size, hand volume and years since menopause. The normal men are found to have an average hand BMC of 25.1 g with a coefficient of variation (CV) of 22%, which is reduced to 12% by normalising for body size using span. The normal women had an average hand BMC of 18.0 g +/- 15%. The CV is reduced to 13% by normalising for span and years post-menopause.

摘要

一种单光子吸收成像技术已被开发出来，用于评估手部骨量，尤其是类风湿性关节炎或支气管哮喘患者。一种改良的直线扫描仪通过在装有7.4GBq 125I源的水浴中进行透射扫描来对手部成像。使用微型计算机计算骨矿物质分布，并根据该分布确定手部的总骨矿物质含量（BMC）。测量的精度（变异系数）为1.9%。对20名男性和58名女性的对照人群进行了研究，以确定手部骨矿物质含量随年龄、性别、体型、手部体积和绝经后年限的正常变化。发现正常男性手部BMC平均为25.1g，变异系数（CV）为22%，通过使用指距对体型进行标准化后，该系数降至12%。正常女性手部BMC平均为18.0g±15%。通过对指距和绝经后年限进行标准化，CV降至13%。