未接受透析的慢性肾脏病患者缺铁性贫血的频率。

Frequency of iron deficiency anaemia in chronic kidney disease patient not on dialysis.

机构信息

Department of Nephrology, The Kidney Centre Post Graduate Training Institute, Karachi, Pakistan.

Department of Nephrology, The Kidney Centre Postgraduate Training Institute, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2022 Jul;72(7):1396-1400. doi: 10.47391/JPMA.4507.

DOI:10.47391/JPMA.4507

PMID:36156567

Abstract

OBJECTIVE

To determine the frequency of iron deficiency anaemia in non-dialysis chronic kidney disease patients.

METHODS

The observational, cross-sectional study was conducted at the Department of Nephrology, The Kidney Centre Post-Graduate Training Institute, Karachi, from April 27 to October 26, 2018, and comprised adult patients of either gender diagnosed with anaemia and estimated glomerular filtration rate <90ml/min. Patient with transferrin saturation <20% were labelled as having iron deficiency anaemia. Data was analysed using SPSS 21.

RESULTS

Of the 366 participants, 185(50.5%) were males and 181(49.5%) were females. The overall mean age was 54.47±14.93 years. The most prevalent comorbid was hypertension 263(71.9%), followed by diabetes mellitus 187(51.1%) and cardiovascular disease 54(14.8%). Besides, 192(52.5%) patients had CKD stage 5 followed by 115(31.4%) and 54(14.8%) with CKD stages 4 and 3, respectively. The mean haemoglobin was 9.17±1.57g/dL. Iron deficiency was found in 285(77.9%) patients.

CONCLUSIONS

Iron deficiency anaemia was found to be highly prevalent and should be screened routinely and managed appropriately.

摘要

目的

确定非透析慢性肾脏病患者缺铁性贫血的发生率。

方法

本观察性、横断面研究于 2018 年 4 月 27 日至 10 月 26 日在卡拉奇肾脏中心研究生培训学院肾脏病科进行，纳入经诊断患有贫血和估计肾小球滤过率<90ml/min 的成年患者。转铁蛋白饱和度<20%的患者被标记为患有缺铁性贫血。使用 SPSS 21 对数据进行分析。

结果

在 366 名参与者中，185 名（50.5%）为男性，181 名（49.5%）为女性。总体平均年龄为 54.47±14.93 岁。最常见的合并症是高血压 263 例（71.9%），其次是糖尿病 187 例（51.1%）和心血管疾病 54 例（14.8%）。此外，192 例（52.5%）患者为 CKD 5 期，115 例（31.4%）和 54 例（14.8%）分别为 CKD 4 期和 3 期。平均血红蛋白为 9.17±1.57g/dL。发现 285 例（77.9%）患者存在缺铁。