[6兆电子伏特平均能量中子对处于有丝分裂周期不同阶段的人淋巴细胞培养物作用的剂量-反应曲线]
[Dose-response curves for the action of 6 MeV mean-energy neutrons on a human lymphocyte culture at different stages of the mitotic cycle].
作者信息
Demina E A
出版信息
Radiobiologiia. 1987 May-Jun;27(3):357-61.
PMID:3615817
Abstract
A linear component was predominant in the dose-response curve characterizing the radiosensitivity of human lymphocyte chromosomes after exposure to fast neutrons (E = 6 MeV) at different mitotic cycle stages. This was indicative of a single-hit mechanism of the formation of chromosome aberrations after the effect of 6 MeV neutrons. It is suggested that the plateau of the dose-response curve at the S-stage may be considered as an indication of repair of damages induced by neutrons at this stage.
摘要
在表征人淋巴细胞染色体在不同有丝分裂周期阶段暴露于快中子（E = 6 MeV）后的放射敏感性的剂量反应曲线中，线性成分占主导。这表明6 MeV中子作用后染色体畸变形成的单打击机制。有人提出，S期剂量反应曲线的平台期可被视为该阶段中子诱导损伤修复的一个指标。
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