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眼科中鼻眶毛霉菌病管理的挑战与陷阱:COVID-19时代的一个突出问题

Challenges and Pitfalls in the Management of Rhino-Orbital Mucormycosis in Ophthalmology: A Highlighted Problem in the COVID-19 Era.

作者信息

Pakdel Farzad, Zand Amin, Sharifi Ali, Asadi Masih, Abri Aghdam Kaveh

机构信息

Department of Oculo-Facial Plastic Surgery, Department of Ophthalmology, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Ophthalmology, Shafa Hospital, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

J Ophthalmic Vis Res. 2022 Aug 15;17(3):424-431. doi: 10.18502/jovr.v17i3.11582. eCollection 2022 Jul-Sep.

DOI:10.18502/jovr.v17i3.11582
PMID:36160102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9493414/
Abstract

Secondary infections in hospitalized and ill patients with coronavirus disease 2019 (COVID-19) are common. One of these life-threatening infectious diseases is rhino-orbital mucormycosis, which made an outbreak recently. This outbreak was mainly caused by the administration of high-dose corticosteroids in patients with COVID-19, especially those with diabetes mellitus. The increased incidence of rhino-orbital mucormycosis in the COVID-19 era presents different challenges for healthcare providers including ophthalmologists who are directly involved in disease management. We summarized the main challenges and recommendations for ophthalmologists on the management of rhino-orbital mucormycosis.

摘要

2019冠状病毒病(COVID-19)住院患者和患病患者的继发感染很常见。其中一种危及生命的传染病是鼻眶毛霉病,该病最近爆发。此次爆发主要是由COVID-19患者,尤其是糖尿病患者使用大剂量皮质类固醇引起的。COVID-19时代鼻眶毛霉病发病率的增加给包括直接参与疾病管理的眼科医生在内的医疗服务提供者带来了不同的挑战。我们总结了眼科医生在鼻眶毛霉病管理方面的主要挑战和建议。

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Global Prevalence of COVID-19-Associated Mucormycosis (CAM): Living Systematic Review and Meta-Analysis.新型冠状病毒肺炎相关毛霉菌病(CAM)的全球患病率:实时系统评价与荟萃分析
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Mycotic infections - mucormycosis and oral candidiasis associated with Covid-19: a significant and challenging association.霉菌感染——毛霉病和与新冠病毒相关的口腔念珠菌病:一种重要且具有挑战性的关联。
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Mycoses. 2021 Oct;64(10):1253-1260. doi: 10.1111/myc.13353. Epub 2021 Jul 24.
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Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102146. doi: 10.1016/j.dsx.2021.05.019. Epub 2021 May 21.
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Microb Pathog. 2021 Sep;158:105018. doi: 10.1016/j.micpath.2021.105018. Epub 2021 Jun 16.
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