Yang Jian, Liu Ying, Sun Xue-Jia, Ai Zhong-Wei, Liu Shi
Department of General Surgery, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang 154003, P.R. China.
Department of Medical Oncology, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, Heilongjiang 161000, P.R. China.
Exp Ther Med. 2022 Aug 30;24(4):641. doi: 10.3892/etm.2022.11578. eCollection 2022 Oct.
The overall incidence of rectal gastrointestinal stromal tumor (RGIST) has risen, but it remains a rare disease. Furthermore, tumor rupture is associated with poor prognosis. The present study reported a rare case of RGIST with indolent biological behavior. The biological behavior of this RGIST was analyzed and its malignant potential was evaluated using a guideline-based risk stratification assessment. The patient was diagnosed with a rectal tumor at the Third Affiliated Hospital of Qiqihar Medical University (Qiqihar, China) in April 2020 and a partial resection biopsy was then performed. This resection counts as a rupture. The biopsy confirmed RGIST and the patient refused further examination and treatment due to economic concerns. However, the patient survives with no tumor progression and metastasis until now, May 2022. In conclusion, based on the present case, tumor rupture in indolent RGIST is not necessarily associated with poor outcome.
直肠胃肠道间质瘤(RGIST)的总体发病率有所上升,但它仍然是一种罕见疾病。此外,肿瘤破裂与预后不良相关。本研究报告了一例具有惰性生物学行为的罕见RGIST病例。分析了该RGIST的生物学行为,并使用基于指南的风险分层评估来评估其恶性潜能。2020年4月,该患者在齐齐哈尔医学院第三附属医院(中国齐齐哈尔)被诊断为直肠肿瘤,随后进行了部分切除活检。此次切除被视为一次破裂。活检确诊为RGIST,患者因经济原因拒绝进一步检查和治疗。然而,截至2022年5月,该患者存活且无肿瘤进展和转移。总之,基于本病例,惰性RGIST中的肿瘤破裂不一定与不良预后相关。