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年轻的 COPD 患者是否接受了足够的流感和肺炎球菌疫苗接种?

Are younger COPD patients adequately vaccinated for influenza and pneumococcus?

机构信息

Department of Physiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41500, Larissa, Greece.

Department of Physiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41500, Larissa, Greece.

出版信息

Respir Med. 2022 Nov;203:106988. doi: 10.1016/j.rmed.2022.106988. Epub 2022 Sep 15.

Abstract

Influenza and pneumococcal pneumonia are major causes of increased morbidity and mortality among elderly and COPD patients. Vaccines against influenza and pneumococcus are recommended for COPD patients according to GOLD 2020 guidelines to prevent serious illnesses. Despite their high morbidity and mortality burden, the vaccination coverage rates remain far below the WHO's recommended targets. In Greece, there are insufficient data on influenza and pneumococcal immunization rates among younger COPD patients. This study investigated whether COPD patients under the age of 65 are adequately vaccinated against influenza and pneumococcus and the factors that influence vaccination rates. 1100 individuals at 22 Primary Health Centers in Central Greece participated in a two-year spirometry monitoring program. Face-to-face interviews were used to collect information regarding demographics, smoking status, comorbidities, respiratory illnesses in the previous two years, and influenza and pneumococcal vaccination coverage from all COPD patients. 117 patients aged 40-65 years old were diagnosed with COPD and 80.3% were males. Only 40.2% of them had received influenza and 32.5% pneumococcus vaccinations. Age, advanced stage of COPD, years on COPD diagnosis, respiratory infection within the previous two years, comorbidity, and smoking cessation are all positively connected with influenza and pneumococcus vaccine coverage in younger COPD patients. Gender, education level, and marital status did not affect influenza and pneumococcus vaccination rates. These vaccination rates among younger COPD patients demonstrate the need for increased awareness and knowledge about the advantages of immunizations in lowering morbidity and mortality.

摘要

流感和肺炎球菌性肺炎是导致老年和 COPD 患者发病率和死亡率增加的主要原因。根据 GOLD 2020 指南,建议 COPD 患者接种流感和肺炎球菌疫苗,以预防严重疾病。尽管它们的发病率和死亡率负担很高,但疫苗接种覆盖率仍远低于世界卫生组织的建议目标。在希腊,关于年轻 COPD 患者的流感和肺炎球菌免疫接种率的数据不足。本研究调查了年龄在 65 岁以下的 COPD 患者是否充分接种了流感和肺炎球菌疫苗,以及影响疫苗接种率的因素。来自希腊中部 22 个初级保健中心的 1100 人参加了为期两年的肺活量监测计划。通过面对面访谈,从所有 COPD 患者那里收集了有关人口统计学、吸烟状况、合并症、前两年的呼吸道疾病以及流感和肺炎球菌疫苗接种覆盖率的信息。诊断为 COPD 的 117 名年龄在 40-65 岁的患者中,有 80.3%为男性。他们中只有 40.2%接种了流感疫苗,32.5%接种了肺炎球菌疫苗。年龄、COPD 晚期、COPD 诊断年限、前两年内的呼吸道感染、合并症和戒烟都与年轻 COPD 患者的流感和肺炎球菌疫苗覆盖率呈正相关。性别、教育程度和婚姻状况均不影响流感和肺炎球菌疫苗接种率。这些年轻 COPD 患者的疫苗接种率表明,需要提高对免疫接种降低发病率和死亡率的好处的认识和了解。

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