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塞尔维亚青光眼患者中与生活质量相关的社会人口学、生活方式及眼部相关因素

Socio-Demographic, lifestyle and eye-related factors associated with quality of life Among people with glaucoma in Serbia.

作者信息

Sencanic Ivan, Gazibara Tatjana, Jaksic Vesna, Grgurevic Anita, Mrakovic Tina, Dotlic Jelena

机构信息

Service d'Ophtalmologie, 478683GHRMSA - Groupe Hospitalier Regional Mulhouse Sud Alsace, France.

Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Serbia.

出版信息

Eur J Ophthalmol. 2022 Sep 26:11206721221128673. doi: 10.1177/11206721221128673.

Abstract

PURPOSE

The purpose of this study was to examine socio-demographic, lifestyle and ophthalmological factors associated with poorer Vision Related Quality of Life (VRQoL) in people with glaucoma.

METHODS

This cross-sectional study included 306 consecutive patients with glaucoma who presented for regular check-ups at the referral center in Belgrade (Serbia) from August 2015 to September 2016. The diagnosis of glaucoma was based on the glaucomatous disc cupping and reproducible visual field impairment on one or both eyes. Quality of life was examined using the validated Glaucoma Quality of Life-15 (GQL-15) and the National Eye Institute Visual Function Questionnaire 25 (NEI VFQ 25).

RESULTS

A series of adjusted linear regression models showed that glaucoma patients with higher educational attainment, who were employed and still driving had better VRQoL. Worse visual acuity and visual field defect, being in later glaucoma stages, having lower intraocular pressure, having two laser interventions as well as having pseudo-exfoliative glaucoma was associated with worse VRQoL. Intake of fewer medications and having had no trabeculectomies on better eye as well as taking less drops per day on worse eye were associated with better VRQoL.

CONCLUSIONS

Several socio-demographic, lifestyle and ocular factors can impact VRQoL in glaucoma patients. Identifying people who are at risk of having worse VRQoL could allow for earlier interventions, such as changes in therapy, undergoing surgery, use of mobility aids etc.

摘要

目的

本研究旨在探讨与青光眼患者较差的视力相关生活质量(VRQoL)相关的社会人口学、生活方式和眼科因素。

方法

这项横断面研究纳入了2015年8月至2016年9月期间在贝尔格莱德(塞尔维亚)转诊中心进行定期检查的306例连续青光眼患者。青光眼的诊断基于青光眼性视盘凹陷以及一只或两只眼睛可重复的视野损害。使用经过验证的青光眼生活质量-15(GQL-15)和美国国立眼科研究所视觉功能问卷25(NEI VFQ 25)对生活质量进行检查。

结果

一系列调整后的线性回归模型显示,受教育程度较高、就业且仍在开车的青光眼患者具有更好的VRQoL。视力和视野缺损较差、处于青光眼晚期、眼压较低、接受过两次激光治疗以及患有假性剥脱性青光眼与较差的VRQoL相关。用药较少、较好眼未进行小梁切除术以及较差眼每天滴眼次数较少与较好的VRQoL相关。

结论

若干社会人口学、生活方式和眼部因素可影响青光眼患者的VRQoL。识别有较差VRQoL风险的人群可允许早期干预,如改变治疗方法、接受手术、使用助行器等。

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