Johansson Lena Havstam, Kalaboukhova Lada, Erhag Hanna Falk, Skoog Ingmar, Zetterberg Madeleine
Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Department of Ophthalmology, Sahlgrenska University Hospital, Region Västra Götaland, Mölndal, Sweden.
Acta Ophthalmol. 2024 Mar;102(2):201-207. doi: 10.1111/aos.15737. Epub 2023 Aug 2.
To evaluate the effect of glaucoma on vision-related quality of life (VRQoL), lifestyle, physical factors and socioeconomic status in a 70-year-old population in Gothenburg, Sweden.
Responses to questionnaires (N = 1182) between groups with and without self-reported glaucoma were analysed. Questionnaires included National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25), Short-Form Health Survey (SF-36), physical activity, socioeconomics, alcohol and tobacco consumption. Balance test and body mass index were also included. About half of the participants were randomized to ophthalmic examination (N = 560), variables were analysed separately according to known and confirmed glaucoma, ocular hypertension and/or cases of previously unknown glaucoma.
Both conventional and Rasch analysis of the NEI VFQ-25 showed that VRQoL was lower for individuals self-reporting glaucoma (p = 0.003/p = 0.024). Regarding general QoL, the participants did not differ apart from people self-reporting glaucoma reported worse general health (p = 0.01). Using logistic regression with lower VRQoL as the dependent variable glaucoma was not a significant predictor of poor VRQoL, odds ratio (OR) 1.83 (95% confidence interval (CI) 0.76-4.39, p = 0.18). Low household income was associated with lower VRQoL (OR 1.63, 95% CI 1.14-2.33, p = 0.01). Socioeconomics, physical activity and lifestyle factors were comparable between the groups (N = 915). Among participants who underwent ophthalmic examination no significant differences were found between glaucoma cases and non-glaucoma cases in relation to VRQoL (N = 560).
Patients with self-reported glaucoma assessed a lower VRQoL but not lower general quality of life. Poorer household income was associated with worse VRQoL. General health was reported low in the glaucoma population but lifestyle or physical factors did not diverge.
评估青光眼对瑞典哥德堡70岁人群的视力相关生活质量（VRQoL）、生活方式、身体因素和社会经济地位的影响。
分析了自我报告患有青光眼和未患青光眼两组人群对问卷（N = 1182）的回答。问卷包括美国国立眼科研究所视觉功能问卷（NEI VFQ - 25）、简短健康调查问卷（SF - 36）、身体活动、社会经济学、酒精和烟草消费情况。还包括平衡测试和体重指数。约一半参与者被随机分配接受眼科检查（N = 560），根据已知和确诊的青光眼、高眼压症和/或先前未知的青光眼病例分别分析变量。
对NEI VFQ - 25进行的传统分析和Rasch分析均显示，自我报告患有青光眼的个体的VRQoL较低（p = 0.003/p = 0.024）。关于总体生活质量，除了自我报告患有青光眼的人报告总体健康状况较差外（p = 0.01），参与者之间没有差异。以较低的VRQoL作为因变量进行逻辑回归分析，青光眼不是VRQoL差的显著预测因素，比值比（OR）为1.83（95%置信区间（CI）为0.76 - 4.39，p = 0.18）。低家庭收入与较低的VRQoL相关（OR为1.63，95%CI为1.14 - 2.33，p = 0.01）。两组之间的社会经济学、身体活动和生活方式因素具有可比性（N = 915）。在接受眼科检查的参与者中，青光眼病例和非青光眼病例在VRQoL方面没有发现显著差异（N = 560）。
自我报告患有青光眼的患者评估的VRQoL较低，但总体生活质量并不低。家庭收入较差与较差的VRQoL相关。青光眼人群报告的总体健康状况较低，但生活方式或身体因素没有差异。
