Reddy Amit K, Kolfenbach Jason R, Palestine Alan G
Department of Ophthalmology.
Division of Rheumatology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Curr Opin Ophthalmol. 2022 Nov 1;33(6):551-556. doi: 10.1097/ICU.0000000000000890. Epub 2022 Sep 16.
This article summarizes the pathophysiology of rheumatoid arthritis and common ocular manifestations that it is associated with: keratoconjunctivitis sicca, episcleritis, scleritis, and peripheral ulcerative keratitis.
Newer biologic agents are being used to effectively treat rheumatoid arthritis and its ocular manifestations.
The eye is a frequent extra-articular site of inflammation in patients with rheumatoid arthritis. Ocular involvement can range from more benign conditions such as keratoconjunctivitis sicca and episcleritis, to potentially vision and globe-threatening diseases like scleritis and peripheral ulcerative keratitis. Clinicians should be aware of these ophthalmic manifestations and the various treatment options that are available. Coordination between ophthalmology and rheumatology is helpful in the treatment of these patients.
本文总结类风湿关节炎的病理生理学及其相关的常见眼部表现:干燥性角结膜炎、巩膜外层炎、巩膜炎和周边溃疡性角膜炎。
新型生物制剂正用于有效治疗类风湿关节炎及其眼部表现。
眼睛是类风湿关节炎患者常见的关节外炎症部位。眼部受累范围可从较为良性的情况如干燥性角结膜炎和巩膜外层炎,到可能威胁视力和眼球的疾病如巩膜炎和周边溃疡性角膜炎。临床医生应了解这些眼科表现及可用的各种治疗选择。眼科与风湿病科之间的协作有助于治疗这些患者。