Cleveland Clinic Orthopedic and Rheumatologic Institute, 1730 West 25th Street, Cleveland, OH 44113, USA.
Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Section of Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA; Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Hand Clin. 2025 Feb;41(1):11-23. doi: 10.1016/j.hcl.2024.07.002. Epub 2024 Oct 15.
Rheumatoid arthritis is a common, chronic autoimmune disease. Its clinical presentation includes both articular and extra-articular manifestations. The past few decades have seen significant developments in our understanding of RA pathogenesis, leading to the development of effective novel targeted treatment options. This article reviews the clinical presentation, pathogenesis, and treatment of RA, along with specific treatment considerations related to reproductive health, vaccination, and the perioperative period.
类风湿关节炎是一种常见的慢性自身免疫性疾病。其临床表现既包括关节表现，也包括关节外表现。在过去几十年中，我们对类风湿关节炎发病机制的认识取得了重大进展，从而开发出了有效的新型靶向治疗方案。本文综述了类风湿关节炎的临床表现、发病机制和治疗方法，以及与生殖健康、疫苗接种和围手术期相关的具体治疗注意事项。
