[氯乙烯诱发的脾和肝血管肉瘤中的微血管病性溶血性贫血、红细胞吞噬作用及消耗性凝血病]
[Microangiopathic hemolytic anemia, erythrophagocytosis and consumption coagulopathy in vinyl chloride-induced hemangiosarcoma of the spleen and liver].
作者信息
Michot F, Bruggisser D, Fehr H, Yurtsever H, Anabitarte M
出版信息
Schweiz Med Wochenschr. 1987 Jun 27;117(26):990-5.
PMID:3616592
Abstract
A case of angiosarcoma of the liver and the spleen following vinyl chloride exposure is described. The main symptoms in clinical diagnosis were microangiopathic hemolysis, disseminated intravascular coagulation, hepatosplenomegaly and exposure to vinyl chloride thirty years ago. It is the first case in which liver and spleen are involved in angiosarcoma due to vinyl chloride exposure. The tumor cells showed angioformative and solid histiocytoid growth with erythrophagocytosis.
摘要
本文描述了一例氯乙烯暴露后发生的肝脾血管肉瘤病例。临床诊断的主要症状为微血管病性溶血、弥散性血管内凝血、肝脾肿大以及30年前有氯乙烯暴露史。这是首例因氯乙烯暴露导致肝脾均发生血管肉瘤的病例。肿瘤细胞呈血管形成性和实性组织细胞样生长，并伴有红细胞吞噬现象。
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