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评估豪登省年轻女性中 HIV 暴露前预防的使用和保留情况。

Assessing HIV Pre-exposure Prophylaxis Uptake and Retention Amongst Young Females in Gauteng Province.

机构信息

Department of Nursing, University of Pretoria, Pretoria, South Africa.

, 44 San Henrique Estate, 2 Rosewood Broadacres, Sandton, 2055, South Africa.

出版信息

AIDS Behav. 2023 Apr;27(4):1182-1187. doi: 10.1007/s10461-022-03855-7. Epub 2022 Sep 27.

DOI:10.1007/s10461-022-03855-7
PMID:36166108
Abstract

Although roll-out of HIV pre-exposure prophylaxis (PrEP) has been reported to have changed contexts of HIV risk in areas where it was well-implemented. The rate of its uptake and retention amongst young females has not been described in Gauteng Province. This paper aimed at assessing PrEP uptake and retention among young females in Gauteng Province. Total of young females who tested HIV across five clinics from 01/January/2017 to 31/December/2020 was 19,671 with 17,937 tested HIV negative. Of the HIV tested negative, PrEP was initiated to 1307 (7%). The analysis revealed that 27% of young females returned for their first follow up visit after PrEP initiation, while third month declined to 14%, fourth month to 11%, and fifth month to 3%, sixth month to 2% and seventh month at 1% and from the eighth month, the rate of follow up was 0%. Uptake and retention of PrEP was low among young females as measured against the total tested HIV negative.

摘要

尽管在实施良好的地区,艾滋病毒暴露前预防(PrEP)的推出已经改变了艾滋病毒风险的背景,但在豪登省,尚未对其在年轻女性中的使用率和保留率进行描述。本文旨在评估豪登省年轻女性中 PrEP 的使用率和保留率。在 2017 年 1 月 1 日至 2020 年 12 月 31 日期间,来自五个诊所的共 19671 名年轻女性接受了艾滋病毒检测,其中 17937 名检测结果为阴性。在这些 HIV 检测阴性的女性中,有 1307 人(7%)开始使用 PrEP。分析显示,在 PrEP 开始后,有 27%的年轻女性返回进行第一次随访,而第三个月下降到 14%,第四个月下降到 11%,第五个月下降到 3%,第六个月下降到 2%,第七个月下降到 1%,第八个月后,随访率为 0%。年轻女性中 PrEP 的使用率和保留率很低,与所有接受 HIV 检测阴性的女性相比。

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本文引用的文献

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J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):593-600. doi: 10.1097/QAI.0000000000002506.
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Uptake and retention on HIV pre-exposure prophylaxis among key and priority populations in South-Central Uganda.乌干达中南地区关键和重点人群中 HIV 暴露前预防的摄入和保留情况。
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Factors influencing uptake, continuation, and discontinuation of oral PrEP among clients at sex worker and MSM facilities in South Africa.
撒哈拉以南非洲地区少女和年轻女性对暴露前预防的接受与使用情况:一项范围综述
AIDS Behav. 2025 Jun;29(6):1876-1896. doi: 10.1007/s10461-025-04656-4. Epub 2025 Feb 28.
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Trial of an mHealth intervention to improve HIV prophylaxis for female sex workers, United Republic of Tanzania.坦桑尼亚联合共和国一项改善女性性工作者 HIV 预防的移动医疗干预试验。
Bull World Health Organ. 2024 Dec 1;102(12):852-860. doi: 10.2471/BLT.24.291516. Epub 2024 Oct 29.
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Uptake of a patient-centred dynamic choice model for HIV prevention in rural Kenya and Uganda: SEARCH SAPPHIRE study.在肯尼亚和乌干达农村地区采用以患者为中心的动态选择模型进行艾滋病毒预防:SEARCH SAPPHIRE 研究。
J Int AIDS Soc. 2023 Jul;26 Suppl 1(Suppl 1):e26121. doi: 10.1002/jia2.26121.
南非性工作者和男男性行为者场所客户口服暴露前预防药物的使用、持续使用和停药的影响因素。
PLoS One. 2020 Apr 30;15(4):e0228620. doi: 10.1371/journal.pone.0228620. eCollection 2020.
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J Int AIDS Soc. 2019 Jul;22 Suppl 4(Suppl Suppl 4):e25306. doi: 10.1002/jia2.25306.
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