Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.
Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA.
Curr Biol. 2022 Sep 26;32(18):R947-R949. doi: 10.1016/j.cub.2022.08.015.
Crosses between closely related species of frogs result in inviable embryos that die following catastrophic cell divisions. A new study identifies defects in centromere maintenance and DNA replication stress as key forces driving this incompatibility.
青蛙的近缘物种杂交会产生没有生命力的胚胎，这些胚胎在灾难性的细胞分裂后死亡。一项新的研究确定了着丝粒维持和 DNA 复制应激的缺陷是导致这种不兼容性的关键因素。
