Jacob Louis, Koyanagi Ai, Haro Josep Maria, Shin Jae Il, Smith Lee, Konrad Marcel, Kostev Karel
Research and Development Unit, Parc Sanitari Sant Joan de Déu/CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona, Spain.
Faculty of Medicine, University of Versailles Saint-Quentin-en-Yvelines, 78180, Montigny-le-Bretonneux, France.
Int Arch Occup Environ Health. 2023 Mar;96(2):303-311. doi: 10.1007/s00420-022-01924-x. Epub 2022 Sep 27.
Little is known about the impact of osteoarthritis on the long-term work participation of working-age adults. Therefore, the goal of this study was to investigate the prevalence of and the factors associated with long-term sick leave in people newly diagnosed with osteoarthritis from Germany.
This retrospective cohort study included patients aged 18-65 years diagnosed with osteoarthritis for the first time (index date) in 1 of 1198 general practices in Germany between 2016 and 2019 (Disease Analyzer database, IQVIA). Patients were considered to be on long-term sick leave if they were absent from work for medical reasons for more than 42 days in the year following the index date. Independent variables included sociodemographic characteristics, type of osteoarthritis, and frequent comorbidities. The association between these variables and long-term sick leave (dependent variable) was studied using an adjusted logistic regression model.
This study included 51,034 patients with osteoarthritis [mean (standard deviation) age 50.8 (9.2) years; 50.9% women]. The prevalence of long-term sick leave was 36.2%. Younger age and male sex were positively and significantly associated with long-term sick leave compared with older age and female sex, respectively. There was also a strong relationship between several comorbidities (e.g., reaction to severe stress, and adjustment disorders, gastritis and duodenitis, and depression) with long-term sick leave.
The prevalence of long-term sick leave was high in this sample of patients newly diagnosed with osteoarthritis from Germany. In this context, interventions should be implemented to increase the long-term working participation of people with osteoarthritis.
骨关节炎对工作年龄成年人长期工作参与度的影响鲜为人知。因此，本研究的目的是调查德国新诊断为骨关节炎患者的长期病假患病率及相关因素。
这项回顾性队列研究纳入了2016年至2019年间在德国1198家普通诊所中首次被诊断为骨关节炎（索引日期）的18至65岁患者（疾病分析器数据库，艾昆纬）。如果患者在索引日期后的一年内因医疗原因缺勤超过42天，则被视为长期病假。自变量包括社会人口统计学特征、骨关节炎类型和常见合并症。使用调整后的逻辑回归模型研究这些变量与长期病假（因变量）之间的关联。
本研究纳入了51034例骨关节炎患者[平均（标准差）年龄50.8（9.2）岁；50.9%为女性]。长期病假的患病率为36.2%。与老年和女性相比，年轻和男性分别与长期病假呈正相关且具有显著相关性。几种合并症（如对严重压力的反应、适应障碍、胃炎和十二指肠炎以及抑郁症）与长期病假之间也存在密切关系。
在德国这个新诊断为骨关节炎的患者样本中，长期病假的患病率很高。在此背景下，应实施干预措施以提高骨关节炎患者的长期工作参与度。
