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营养管理和教育在自闭症治疗中的重要性。

The importance of nutritional management and education in the treatment of autism.

机构信息

Wroclaw University of Environmental and Life Sciences, Faculty of Biotechnology and Food Sciences, Department of Functional Food Products Development, Chełmońskiego 37, 51-630 Wroclaw, Poland.

Wroclaw Medical University, Faculty of Pharmacy, Department of Dietetics, Borowska 211, 50-556 Wrocław, Poland.

出版信息

Rocz Panstw Zakl Hig. 2022;73(3):247-258. doi: 10.32394/rpzh.2022.0218.


DOI:10.32394/rpzh.2022.0218
PMID:36169265
Abstract

Autism spectrum disorders (ASDs) are an early-onset neurodevelopmental disorders. The key symptoms of ASD include social deficits, verbal and non-verbal communication deficits, and restricted, repetitive patterns of behaviour, interests, or activities. Dietary patterns have been evidenced to be related to maternal nutritional status that might lead to different metabolic conditions, and maternal metabolic dysfunction has been observed to be associated with ASD. Furthermore growing evidence suggests that the gut microbiota has a role in the pathophysiology of ASD. Differences in composition of the gastrointestinal (GI) microbiota in children with ASD compared to unaffected siblings and/or healthy unrelated controls have been reported in various studies. The above-mentioned ASD factors and symptoms can be regulated by proper nutrition. The importance of nutrition and its possible impact on ASD patients is key to integral therapy. According to numerous research studies, various nutritional approaches succeeded in reducing the severity of patients' core ASD symptoms. The numerous options for diet that is used in the ASD therapy, as described in the scientific literature, are related to the problem of choosing an appropriate nutritional treatment. Each nutrition programme needs to be personalised and tailored to an individual patient. The aim of the paper is to review the available literature on dietary interventions in children with ASD and provide up-to-date evidence.

摘要

自闭症谱系障碍(ASD)是一种早期发生的神经发育障碍。ASD 的主要症状包括社交缺陷、言语和非言语交流障碍,以及受限的、重复的行为、兴趣或活动模式。饮食模式与母体营养状况有关,这可能导致不同的代谢状况,而母体代谢功能障碍与 ASD 有关。此外,越来越多的证据表明,肠道微生物群在 ASD 的病理生理学中起作用。在各种研究中,已经报道了 ASD 儿童与未受影响的兄弟姐妹和/或健康无关的对照组相比,胃肠道(GI)微生物群的组成存在差异。上述 ASD 因素和症状可以通过适当的营养来调节。营养的重要性及其对 ASD 患者的可能影响是整体治疗的关键。根据许多研究,各种营养方法成功地减轻了患者核心 ASD 症状的严重程度。在 ASD 治疗中使用的多种饮食选择,如科学文献中所述,与选择适当营养治疗的问题有关。每个营养计划都需要针对个体患者进行个性化和定制。本文的目的是回顾自闭症儿童饮食干预的现有文献,并提供最新的证据。

相似文献

[1]
The importance of nutritional management and education in the treatment of autism.

Rocz Panstw Zakl Hig. 2022

[2]
Microbiome and nutrition in autism spectrum disorder: current knowledge and research needs.

Nutr Rev. 2016-12

[3]
How nutritional status, diet and dietary supplements can affect autism. A review.

Rocz Panstw Zakl Hig. 2013

[4]
Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions.

Nutrients. 2019-11-18

[5]
The complex interplay between autism spectrum disorder and gut microbiota in children: A comprehensive review.

Behav Brain Res. 2024-9-13

[6]
Gastrointestinal involvement of autism spectrum disorder: focus on gut microbiota.

Expert Rev Gastroenterol Hepatol. 2021-6

[7]
The Role of Gut Microbiota in Gastrointestinal Symptoms of Children with ASD.

Medicina (Kaunas). 2019-7-26

[8]
Narrative Review: The Effect of Vitamin A Deficiency on Gut Microbiota and Their Link with Autism Spectrum Disorder.

J Diet Suppl. 2024

[9]
Overview of Nutritional Therapy for Autism Spectrum Disorder.

Adv Neurobiol. 2020

[10]
Can we reduce autism-related gastrointestinal and behavior problems by gut microbiota based dietary modulation? A review.

Nutr Neurosci. 2021-5

引用本文的文献

[1]
Knowledge, attitudes, and practices of healthcare professionals regarding medical nutrition therapy for type 2 diabetes: a multicenter cross-sectional study.

Endocrine. 2025-6-21

[2]
Nutritional Approaches in Autism Spectrum Disorder: A Scoping Review.

Curr Nutr Rep. 2025-4-22

[3]
Feeding-Related Early Signs of Autism Spectrum Disorder: A Narrative Review.

J Pers Med. 2024-8-2

[4]
A Review of the Nutritional Approach and the Role of Dietary Components in Children with Autism Spectrum Disorders in Light of the Latest Scientific Research.

Nutrients. 2023-11-21

[5]
Ratings of the Effectiveness of 13 Therapeutic Diets for Autism Spectrum Disorder: Results of a National Survey.

J Pers Med. 2023-9-29

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