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鼠伤寒沙门氏菌中由麦芽糖诱导产生的主要外膜蛋白。

Major outer membrane protein in Salmonella typhimurium induced by maltose.

作者信息

Palva E T

出版信息

J Bacteriol. 1978 Oct;136(1):286-94. doi: 10.1128/jb.136.1.286-294.1978.

DOI:10.1128/jb.136.1.286-294.1978
PMID:361696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC218659/
Abstract

A maltose-induced major outer membrane protein (the 44K protein) is demonstrated in Salmonella typhimurium. This protein resembles the lambda receptor of Escherichia coli in its location, induction properties, apparent molecular weight, and association with the peptidoglycan layer of the cell wall. The 44K protein is missing in certain Salmonella Mal- mutants, which are also missing a protein analogous to the maltose-binding protein of E. coli. Thus, these mutants may be defective in the control of maltose genese in Salmonella. The proteins appear to be closely related, as indicated by cross-reaction of the Salmonella protein with the antiserum raised against the lambda receptor; however, they are not identical, since the peptide patterns obtained after limited proteolysis are completely different. Bacteriophage lambda does not use the 44K protein as a receptor.

摘要

在鼠伤寒沙门氏菌中证实了一种麦芽糖诱导的主要外膜蛋白（44K蛋白）。这种蛋白在其位置、诱导特性、表观分子量以及与细胞壁肽聚糖层的关联方面类似于大肠杆菌的λ受体。某些沙门氏菌麦芽糖缺陷型（Mal-）突变体中缺少44K蛋白，这些突变体也缺少一种类似于大肠杆菌麦芽糖结合蛋白的蛋白。因此，这些突变体在沙门氏菌麦芽糖基因的调控方面可能存在缺陷。正如沙门氏菌蛋白与针对λ受体产生的抗血清的交叉反应所表明的，这些蛋白似乎密切相关；然而，它们并不相同，因为有限蛋白酶解后获得的肽图谱完全不同。噬菌体λ并不将44K蛋白用作受体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/11d178eabf01/jbacter00287-0300-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/366a0d233b86/jbacter00287-0296-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/3dc2defceabb/jbacter00287-0297-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/11a528715f89/jbacter00287-0298-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/580aa045aa22/jbacter00287-0299-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/11d178eabf01/jbacter00287-0300-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/366a0d233b86/jbacter00287-0296-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/3dc2defceabb/jbacter00287-0297-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/11a528715f89/jbacter00287-0298-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/580aa045aa22/jbacter00287-0299-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8231/218659/11d178eabf01/jbacter00287-0300-a.jpg

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Site-directed mutagenesis of tyrosine 118 within the central constriction site of the LamB (Maltoporin) channel of Escherichia coli. I. Effect on ion transport.大肠杆菌LamB（麦芽糖孔蛋白）通道中央收缩位点内酪氨酸118的定点诱变。I. 对离子转运的影响。
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Cloning of the regulatory locus ompB of Salmonella typhimurium LT-2. I. Isolation of the ompR gene and identification of its gene product.鼠伤寒沙门氏菌LT-2调节位点ompB的克隆。I. ompR基因的分离及其基因产物的鉴定。
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Genetic analysis of the maltose A region in Escherichia coli.大肠杆菌中麦芽糖A区域的遗传分析。
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A method for measuring chemotaxis and use of the method to determine optimum conditions for chemotaxis by Escherichia coli.一种测量趋化性的方法以及使用该方法确定大肠杆菌趋化性最佳条件的应用。
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8
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Protein composition of the outer membrane of Salmonella typhimurium: effect of lipopolysaccharide mutations.鼠伤寒沙门氏菌外膜的蛋白质组成：脂多糖突变的影响。
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