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气道上皮失调在哮喘患者应对呼吸道病毒感染中的关键作用。

Key role of dysregulated airway epithelium in response to respiratory viral infections in asthma.

作者信息

Moheimani Fatemeh, Shahdab Nafeesa, Cummings Stephen, Hansbro Philip M, Ward Christopher

机构信息

School of Health and Life Sciences, Teesside University, Middlesbrough, UK.

National Horizons Centre, Teesside University, Darlington, UK.

出版信息

ERJ Open Res. 2022 Sep 26;8(3). doi: 10.1183/23120541.00314-2022. eCollection 2022 Jul.

DOI:10.1183/23120541.00314-2022
PMID:36171982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9511154/
Abstract

https://bit.ly/3yDgiX1.

摘要

https://bit.ly/3yDgiX1. （此为链接，无法准确翻译其内容，保留原文形式）

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Reply: Key role of dysregulated airway epithelium in response to respiratory viral infections in asthma.回复：气道上皮功能失调在哮喘患者对呼吸道病毒感染的反应中的关键作用。
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Therapeutic targets in lung tissue remodelling and fibrosis.肺组织重塑和纤维化的治疗靶点。
Pharmacol Ther. 2021 Sep;225:107839. doi: 10.1016/j.pharmthera.2021.107839. Epub 2021 Mar 25.
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Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPD.气道上皮细胞免疫在哮喘和 COPD 患者鼻病毒感染期间被延迟。
Front Immunol. 2020 May 15;11:974. doi: 10.3389/fimmu.2020.00974. eCollection 2020.
4
Rhinovirus infections change DNA methylation and mRNA expression in children with asthma.鼻病毒感染改变哮喘儿童的 DNA 甲基化和 mRNA 表达。
PLoS One. 2018 Nov 28;13(11):e0205275. doi: 10.1371/journal.pone.0205275. eCollection 2018.
5
Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics.甲型流感病毒感染会扰乱哮喘患者上皮细胞中 microRNA-22 及其靶标 CD147 和 HDAC4 的表达。
Respir Res. 2018 Aug 2;19(1):145. doi: 10.1186/s12931-018-0851-7.
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The genetic and epigenetic landscapes of the epithelium in asthma.哮喘中上皮细胞的遗传和表观遗传图谱。
Respir Res. 2016 Sep 22;17(1):119. doi: 10.1186/s12931-016-0434-4.
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Clin Immunol. 2014 Mar;151(1):1-15. doi: 10.1016/j.clim.2013.12.003. Epub 2013 Dec 14.
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