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Activating translation by phase separation: a novel mechanism for driving spermiogenesis.

作者信息

Zhang Wenjing, Wang Yang

机构信息

Institute of Cancer Stem Cell, Dalian Medical University, Dalian, 116044, China.

出版信息

Sci China Life Sci. 2023 Feb;66(2):418-420. doi: 10.1007/s11427-022-2205-x. Epub 2022 Sep 27.

DOI:10.1007/s11427-022-2205-x
PMID:36173540
Abstract
摘要

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本文引用的文献

1
LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs.FXR1的液-液相分离通过激活储存mRNA的翻译来驱动精子发生。
Science. 2022 Aug 12;377(6607):eabj6647. doi: 10.1126/science.abj6647.
2
Liquid-liquid phase separation: a principal organizer of the cell's biochemical activity architecture.液-液相分离：细胞生化活性架构的主要组织者。
Trends Pharmacol Sci. 2021 Oct;42(10):845-856. doi: 10.1016/j.tips.2021.07.003. Epub 2021 Aug 6.
3
It's not just a phase: function and characteristics of RNA-binding proteins in phase separation.
并非只是一个阶段：相分离中 RNA 结合蛋白的功能和特性。
Nat Struct Mol Biol. 2021 Jun;28(6):465-473. doi: 10.1038/s41594-021-00601-w. Epub 2021 Jun 7.
4
Phase Separation during Germline Development.生殖系发育中的相分离。
Trends Cell Biol. 2021 Apr;31(4):254-268. doi: 10.1016/j.tcb.2020.12.004. Epub 2021 Jan 14.
5
Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases.生物学中的液-液相分离：机制、生理功能与人类疾病
Sci China Life Sci. 2020 Jul;63(7):953-985. doi: 10.1007/s11427-020-1702-x. Epub 2020 Apr 30.
6
Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.突触后致密物中的相变是突触复合体形成和突触可塑性的基础。
Cell. 2016 Aug 25;166(5):1163-1175.e12. doi: 10.1016/j.cell.2016.07.008.
7
Translation. An RNA biosensor for imaging the first round of translation from single cells to living animals.翻译。一种用于对从单细胞到活体动物的首轮翻译进行成像的RNA生物传感器。
Science. 2015 Mar 20;347(6228):1367-671. doi: 10.1126/science.aaa3380.
8
Control of messenger RNA fate by RNA-binding proteins: an emphasis on mammalian spermatogenesis.RNA结合蛋白对信使核糖核酸命运的调控：重点关注哺乳动物精子发生过程
J Androl. 2012 May-Jun;33(3):309-37. doi: 10.2164/jandrol.111.014167. Epub 2011 Jul 14.
9
Unique chromatin remodeling and transcriptional regulation in spermatogenesis.精子发生过程中独特的染色质重塑与转录调控。
Science. 2002 Jun 21;296(5576):2176-8. doi: 10.1126/science.1070963.