Abrashev N, Georgiev P, Angelov G, Ivanov V
Vet Med Nauki. 1987;24(2):46-51.
Six calves were used to formulate a model of liver injury, following up the activity of the serum enzymes LAP, ALD, AP, GPT, GOT, OKT, and guanase. Studied were also the contents of blood sugar, calcium, phosphorus as well as some indices of the lipid metabolism. It was found that even with the least severe injuries of the liver there was a considerable rise of the OKT, guanase, GOT, GPT, and LAP activity. It is believed that the enzyme changes alone could serve as a specific index to detect the earliest injury of the liver.
选用6头小牛建立肝损伤模型,同时跟踪血清酶LAP、ALD、AP、GPT、GOT、OKT和鸟嘌呤酶的活性。还研究了血糖、钙、磷的含量以及脂质代谢的一些指标。结果发现,即使是肝脏最轻微的损伤,OKT、鸟嘌呤酶、GOT、GPT和LAP的活性也会显著升高。人们认为,仅酶的变化就可以作为检测肝脏最早损伤的一个特异性指标。