Borovskaia T G, Udintsev S N, Zueva E P, Fomina T I, Neĭshtadt E L
Vopr Onkol. 1987;33(7):60-4.
The study was concerned with an attempt at reducing the acute toxic effect of 5-fluorouracil (5-FU) on gut mucosa in mice with Ehrlich ascites tumors. An official preparation of plantain sap was shown to ward off this effect and to contribute to the normalising of certain parameters of epithelial cells. The DNA level of tumor cells showed a more drastic decline after combined treatment with 5-FU and the preparation than after the cytostatic drug alone.
该研究旨在尝试减轻5-氟尿嘧啶(5-FU)对患有艾氏腹水瘤的小鼠肠道黏膜的急性毒性作用。结果表明,一种官方制备的车前草汁液能够抵御这种作用,并有助于使上皮细胞的某些参数恢复正常。与单独使用细胞抑制药物相比,5-FU与该制剂联合治疗后肿瘤细胞的DNA水平下降更为显著。