Nishimura Takeshi, Suga Masafumi, Nakao Atsunori, Ishihara Satoshi, Naito Hiromichi
Department of Emergency and Critical Care Medicine Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama Japan.
Department of Emergency and Critical Care Medicine Hyogo Emergency Medical Center Nishinomiya Japan.
Acute Med Surg. 2022 Sep 16;9(1):e786. doi: 10.1002/ams2.786. eCollection 2022 Jan-Dec.
Survival of traumatic out-of-hospital cardiac arrest (OHCA) is poor. Early use of advanced airway management (AAM) techniques, including endotracheal intubation and supraglottic devices, are expected to contribute to the improved survival of these patients. The aim of this study was to determine whether prehospital use of AAM improves the outcomes for emergency medical service (EMS)-witnessed traumatic OHCA.
A nationwide retrospective study was carried out. Trauma patients with EMS-witnessed cardiac arrest who received cardiopulmonary resuscitation during transport were included. Patients younger than 16 years and those with missing data were excluded. We compared two groups using propensity score matching. The primary outcome was survival to discharge. The secondary outcome was return of spontaneous circulation (ROSC) on hospital arrival. A logistic regression model was used to calculate odds ratios (OR) and confidence intervals (CI).
After propensity score matching, 1,346 patients were enrolled (AAM 673 versus non-AAM 673). Forty-four AAM cases (6.5%) and 39 non-AAM cases (5.8%) survived. Logistic regression analysis did not show a contribution of AAM for survival to discharge (AAM 44/673 (6.5%), non-AAM 39/673 (5.8%); OR 1.12; 95% CI, 0.70-1.76; = 0.64). However, AAM improved ROSC on admission (AAM 141/673 (21.0%), non-AAM 77/673 (11.4%); OR 2.05; 95% CI, 1.51-2.78; < 0.001). This tendency was consistent throughout our subgroup analysis categorized by body region of the severe injury (head trauma, torso trauma, and extremity/spine trauma).
Prehospital AAM among EMS-witnessed traumatic OHCA patients was not associated with survival to discharge; however, ROSC on hospital admission improved for the AAM patients.
院外创伤性心脏骤停(OHCA)患者的生存率较低。早期使用包括气管插管和声门上装置在内的高级气道管理(AAM)技术有望提高这些患者的生存率。本研究的目的是确定院前使用AAM是否能改善急诊医疗服务(EMS)见证的创伤性OHCA患者的预后。
进行了一项全国性的回顾性研究。纳入在转运过程中接受心肺复苏的EMS见证心脏骤停的创伤患者。排除16岁以下患者及数据缺失者。我们使用倾向评分匹配比较两组。主要结局是出院生存率。次要结局是入院时自主循环恢复(ROSC)。使用逻辑回归模型计算比值比(OR)和置信区间(CI)。
倾向评分匹配后,纳入1346例患者(AAM组673例,非AAM组673例)。44例AAM组患者(6.5%)和39例非AAM组患者(5.8%)存活。逻辑回归分析未显示AAM对出院生存有影响(AAM组44/673例(6.5%),非AAM组39/673例(5.8%);OR 1.12;95%CI,0.70 - 1.76;P = 0.64)。然而,AAM提高了入院时的ROSC(AAM组141/673例(21.0%),非AAM组77/673例(11.4%);OR 2.05;95%CI,1.51 - 2.78;P < 0.001)。在按重伤身体部位分类的亚组分析中,这种趋势一致(头部创伤、躯干创伤和四肢/脊柱创伤)。
EMS见证的创伤性OHCA患者院前使用AAM与出院生存无关;然而,AAM组患者入院时的ROSC有所改善。