Braginskaia F I, Sadykhova S Kh
Biofizika. 1979 Mar-Apr;24(2):325-6.
The ultrasonic absorption of nucleic acids in water solutions was studied by the pulse ultrasonic technique depending on pH, at frequency 12 mHz T = 20 dedrees C. The obtained data show the occurrence of structural relaxation in DNA solutions caused by the proton exchange and transfer reactions with the extremal pH at 2.5 and 11.7. Possible mechanisms of the excess ultrasonic absorption were discussed concerning the protolytic processes with the charged DNA groups (N--P1 exchange and the hydrolysis of lactam groups at acid and alkaline pH correspondingly).
采用脉冲超声技术，在频率12兆赫、温度20摄氏度的条件下，研究了核酸在水溶液中的超声吸收与pH值的关系。所得数据表明，在pH值为2.5和11.7时，由于质子交换和转移反应，DNA溶液中发生了结构弛豫。讨论了超声吸收过量的可能机制，涉及带电荷的DNA基团的质子转移过程（分别为酸性和碱性pH条件下的N-P1交换和内酰胺基团水解）。
