Samplin Erin, Grzenda Adrienne, Burns Alaina Vandervoort
Department of Psychiatry & Biobehavioral Sciences David Geffen School of Medicine at UCLA Los Angeles CA USA.
West Los Angeles VA Medical Center Los Angeles CA USA.
Psychiatr Res Clin Pract. 2022 Jun 10;4(3):74-79. doi: 10.1176/appi.prcp.20210030. eCollection 2022 Fall.
Intensive outpatient programs (IOPs) are rarely designed specifically to treat psychosis. In 2016 UCLA established the Thought Disorders Intensive Outpatient Program (TD IOP), combining a time-limited, group-based intervention called cognitive behavioral social skills training (CBSST) and medication management to treat individuals with psychosis. The purpose of this study is to assess the feasibility of developing an IOP for individuals with psychosis and the effectiveness of the program in improving psychotic symptom severity.
Adults were referred to the TD IOP from inpatient and outpatient settings. Programming included 3 hours of CBSST and 6 hours of additional groups weekly as well as individual psychiatry and social work services. Primary outcomes were symptom changes as measured at intake and discharge by the Clinician-Rated Dimensions of Psychosis Symptom Severity scale. Program feedback was solicited from a small subset of patients.
Of the 92 enrolled subjects, 71 completed the program (77.2%). Average length of stay was 52 ± 30 days across all enrolled. Participants showed significant ( < 0.05) improvement with small-moderate effect sizes across five of eight psychosis symptom domains (hallucinations, delusions, disorganized speech, depression, and mania). Patient-reported program satisfaction was high (86.6 ± 12.7 score, range 0-100).
The current study indicates that targeted treatment for psychosis is successful within an IOP framework, with minimal additional training required for Master's level clinicians. Participants demonstrated significant symptomatic relief from group-based, time-limited treatment. Further work is needed to determine the full range of program benefits on patient well-being and illness morbidity.
强化门诊项目(IOPs)很少专门设计用于治疗精神病。2016年,加州大学洛杉矶分校设立了思维障碍强化门诊项目(TD IOP),将一种名为认知行为社交技能训练(CBSST)的限时、小组干预与药物管理相结合,以治疗患有精神病的个体。本研究的目的是评估为患有精神病的个体开发IOP的可行性以及该项目在改善精神病症状严重程度方面的有效性。
成人从住院和门诊环境中转介至TD IOP。项目安排包括每周3小时的CBSST和6小时的额外小组活动,以及个体精神病学和社会工作服务。主要结果是通过临床医生评定的精神病症状严重程度维度量表在入组时和出院时测量的症状变化。从一小部分患者中征求项目反馈。
在92名入组受试者中,71人完成了项目(77.2%)。所有入组者的平均住院时间为52±30天。参与者在八个精神病症状领域中的五个(幻觉、妄想、言语紊乱、抑郁和躁狂)显示出显著(<0.05)改善,效应大小为小到中等。患者报告的项目满意度很高(得分86.6±12.7,范围0 - 100)。
当前研究表明,在IOP框架内针对精神病的靶向治疗是成功的,硕士水平的临床医生所需的额外培训最少。参与者通过基于小组的限时治疗表现出症状明显缓解。需要进一步开展工作以确定该项目对患者幸福感和疾病发病率的全面益处。