Lam John C, Stokes William
Division of Infectious Diseases, Department of Medicine, University of California Los Angeles.
Provincial Laboratory for Public Health, Alberta Precision Laboratories, Alberta, Canada; Department of Pathology and Laboratory Medicine; Division of Infectious Diseases, Department of Medicine, University of Alberta, Edmonton, Canada.
Am J Med. 2023 Jan;136(1):19-26. doi: 10.1016/j.amjmed.2022.09.017. Epub 2022 Sep 28.
Staphylococcus aureus bacteremia is common and associated with fatality rates approximating 25%. We provide a brief overview of S. aureus bacteremia from a clinical and microbiological lens and review the relevant evidence and literature gaps in its management. Using a case-based approach, evidence and clinical judgement are meshed to highlight and justify the 5 core interventions that ought to be performed for all cases of S. aureus bacteremia: 1) appropriate anti-staphylococcal therapy, 2) screening echocardiography, 3) assessment for metastatic phenomena and source control, 4) decision on duration of antimicrobial therapy, and 5) Infectious Diseases consultation.
金黄色葡萄球菌菌血症很常见，死亡率约为25%。我们从临床和微生物学角度简要概述金黄色葡萄球菌菌血症，并回顾其管理方面的相关证据和文献空白。采用基于病例的方法，将证据与临床判断相结合，以突出并论证针对所有金黄色葡萄球菌菌血症病例都应实施的5项核心干预措施：1）适当的抗葡萄球菌治疗；2）筛查性超声心动图检查；3）评估转移性现象和源头控制；4）决定抗菌治疗的持续时间；5）咨询感染病科。
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