Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA.
Neonatal Medicine, Children's Minnesota, Minneapolis, MN.
Neoreviews. 2022 Oct 1;23(10):e661-e676. doi: 10.1542/neo.23-10-e661.
Advances in ventilation strategies for infants in the NICU have led to increased survival of extremely preterm infants. More than 75% of infants born at less than or equal to 27 weeks' gestation require initial mechanical ventilation for survival due to developmental immaturity of their lungs and respiratory drive. Various ventilators using different technologies and involving multiple management strategies are available for use in this population. Centers across the world have successfully used conventional, high-frequency oscillatory and high-frequency jet ventilation to manage respiratory failure in extremely preterm infants. This review explores the existing evidence for each mode of ventilation and the importance of individualizing ventilator management strategies when caring for extremely preterm infants.
新生儿重症监护病房中通气策略的进步使极早产儿的存活率提高。由于肺部和呼吸驱动力发育不成熟，超过 75%的胎龄小于或等于 27 周的婴儿需要初始机械通气才能存活。为该人群提供了各种使用不同技术和涉及多种管理策略的通气机。世界各地的中心已经成功地使用常规、高频振荡和高频喷射通气来治疗极早产儿的呼吸衰竭。本综述探讨了每种通气模式的现有证据，以及在护理极早产儿时个体化通气管理策略的重要性。
