Bardy A H
Acta Neurol Scand. 1987 May;75(5):356-60. doi: 10.1111/j.1600-0404.1987.tb05459.x.
154 pregnancies of 140 epileptic patients were observed in a prospective study. The number of seizures during pregnancy and 3 first puerperal months was compared with the number of seizures during the 12 months preceding pregnancy. An increase in the number of seizures was noticed in 32% of the cases, a decrease in 14% and unchanged frequency in 23% of the cases, 31% being seizure-free during the study period. The highest incidence of major convulsive seizures occurred during the last trimester of pregnancy, while the incidence of complex partial seizures was highest during puerperium. No factors were found which may predict the increase in seizures.
在一项前瞻性研究中，观察了140例癫痫患者的154次妊娠情况。将孕期及产后前3个月的癫痫发作次数与妊娠前12个月的癫痫发作次数进行了比较。结果发现，32%的病例癫痫发作次数增加，14%的病例发作次数减少，23%的病例发作频率不变，31%的病例在研究期间无癫痫发作。重度惊厥发作的最高发生率出现在妊娠晚期，而复杂部分性发作的发生率在产褥期最高。未发现可预测癫痫发作增加的因素。
