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前瞻性随机研究比较内窥镜下牵开器松解与开放松解腕管和肘管综合征。

A prospective randomized study comparing retractor-endoscopic vs. open release of carpal tunnel and cubital tunnel syndromes.

机构信息

Department of Neurosurgery, University Hospital Giessen, Giessen, Germany.

Department of Neurosurgery, University Hospital Giessen, Giessen, Germany.

出版信息

Clin Neurol Neurosurg. 2022 Nov;222:107437. doi: 10.1016/j.clineuro.2022.107437. Epub 2022 Sep 19.

Abstract

OBJECTIVE

To evaluate the neurological and neurophysiological outcomes of retractor-endoscopic versus open release in carpal tunnel syndrome (rCTS and oCTS, respectively) and cubital tunnel syndrome (rCbTS and oCbTS, respectively) at 3- and 12-month follow-up.

METHODS

Between 2013 and 2017, 80 patients were prospectively blindly randomized. McGowan scores were used for preoperative grading and outcomes were assessed using a modified Bishop rating system (BRS). Furthermore, incapacity to work, duration of postoperative pain, hypoesthesia, atrophy, subjective weakness, and a subjective assessment of the operative result were analyzed. The differences in the cohorts were evaluated with t-tests and ANOVAs as parametric tests and Kruskal-Wallis and Mann-Whitney U tests as nonparametric tests.

RESULTS

The 80 patients underwent retractor-endoscopic or open decompression of the median or ulnar nerve. The rCTS group exhibited significant improvements in neurophysiological data (P = 0.032), shorter periods of postoperative pain (P = 0.03), and less discomfort (P = 0.005), as well as significantly better BRS results after 3 months compared with the oCTS group (P = 0.005). Between the oCbS and rCbTS groups, no significant differences were observed (P > 0.05). Regarding improvements in McGowan scores, no statistically significant differences were observed between the rCTS and oCTS groups after 3 months (P = 0.52) or 12 months (P = 0.86), nor were any observed between the rCbTS and oCbTS groups after 3 months (P = 0.88) or 12 months (P = 0.10).

CONCLUSION

Significantly superior results were obtained at short-term follow-up for rCTS, whereas no superiority was found for rCbTS release. This study concluded that this endoscopic procedure is safe as well as and effective and has the potential to achieve better results in carpal tunnel syndrome compared with conventional methods.

摘要

目的

评估腕管综合征(rCTS 和 oCTS)和肘管综合征(rCbTS 和 oCbTS)经内窥镜下牵开器与开放式松解术后 3 个月和 12 个月的神经学和神经生理学结果。

方法

2013 年至 2017 年间,前瞻性、盲法、随机分配 80 名患者。术前采用 McGowan 评分进行分级,术后采用改良 Bishop 评分系统(BRS)进行评估。此外,分析了工作能力丧失、术后疼痛持续时间、感觉迟钝、萎缩、主观无力和手术结果的主观评估。采用 t 检验、方差分析(参数检验)和 Kruskal-Wallis 和 Mann-Whitney U 检验(非参数检验)对两组间的差异进行评估。

结果

80 名患者接受了内窥镜下或开放式正中神经或尺神经松解术。rCTS 组在神经生理学数据方面有显著改善(P=0.032),术后疼痛持续时间较短(P=0.03),不适程度较低(P=0.005),术后 3 个月 BRS 结果显著优于 oCTS 组(P=0.005)。oCbS 组和 rCbTS 组之间无显著差异(P>0.05)。3 个月和 12 个月时,rCTS 组和 oCTS 组的 McGowan 评分改善无统计学差异(3 个月:P=0.52;12 个月:P=0.86),rCbTS 组和 oCbTS 组间也无统计学差异(3 个月:P=0.88;12 个月:P=0.10)。

结论

rCTS 短期随访结果显著优于传统方法,而 rCbTS 松解术则无优势。本研究认为,与传统方法相比,这种内窥镜手术安全有效,可能在腕管综合征方面取得更好的结果。

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