Ataturk University, Yakutiye, Turkey.
Acta Neurol Belg. 2023 Oct;123(5):1861-1868. doi: 10.1007/s13760-022-02097-7. Epub 2022 Oct 2.
Arachnoid granulations (AG) can be located anywhere outside the dural sinuses. Their presence is thought to be associated with idiopathic intracranial hypertension (IIH) and cerebrospinal fluid (CSF) leaks. It was aimed to evaluate the intraosseous AGs located in the middle and anterior cranial fosses in detail with three-dimensional T2-SPACE (Sampling Perfection with Application optimized Contrasts using different flip angle Evolution-Siemens) imaging and to investigate their clinical significance.
Sixty-five intraosseous AG of 46 patients were included in this retrospective study. The highest diameter, bone indentation degree (in the inner tabula, diploe distance, reaching and exceeding the outer tabula), content (CSF/+parenchyma) of each AG were evaluated by 2 experienced radiologists. In addition, the presence of other MRI findings supporting IIH was examined.
Additional signs of IIH were detected in 25 patients, and they were statistically significantly more common in the middle cranial fossa. Parenchymal herniation (in four patients) was more common in the young population.
Intraosseous AGs can be evaluated in detail with T2-SPACE imaging. Determining intraosseous AG is very important both as an indicator of IIH and in terms of its content. T2-SPACE imaging is superior to CT and conventional sequences in this regard.
蛛网膜颗粒（AG）可位于硬脑膜窦外的任何部位。它们的存在被认为与特发性颅内高压（IIH）和脑脊液（CSF）漏有关。本研究旨在通过三维 T2-SPACE（采用不同翻转角的采样完美应用优化对比-西门子）成像详细评估中颅窝和前颅窝的骨内 AG，并探讨其临床意义。
本回顾性研究纳入了 46 例患者的 65 个骨内 AG。由 2 名有经验的放射科医生评估每个 AG 的最大直径、骨凹陷程度（内板、板障距离、到达并超过外板）、内容物（CSF/+实质）。此外，还检查了支持 IIH 的其他 MRI 发现。
在 25 例患者中发现了 IIH 的其他征象，并且在中颅窝中更为常见，具有统计学意义。在年轻患者中，实质疝出（4 例）更为常见。
T2-SPACE 成像可详细评估骨内 AG。确定骨内 AG 不仅作为 IIH 的指标很重要，而且其内容也很重要。在这方面，T2-SPACE 成像优于 CT 和常规序列。
