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支气管肺发育不良早产儿的静息能量消耗。

Resting energy expenditure in preterm newborns with bronchopulmonary dysplasia.

机构信息

Neonatology Department, Instituto Fernandes Figueira, Fundação Oswaldo Cruz, FIOCRUZ, Brazil.

Professor at the Applied Clinical Research Post-graduation in Instituto Fernandes Figueira, Fundação Oswaldo Cruz, FIOCRUZ, Brazil.

出版信息

Clin Nutr ESPEN. 2022 Oct;51:478-480. doi: 10.1016/j.clnesp.2022.09.002. Epub 2022 Sep 11.

DOI:10.1016/j.clnesp.2022.09.002

PMID:36184245

Abstract

BACKGROUND & AIMS: Greater energy expenditure is reported in newborns with bronchopulmonary dysplasia (BPD). This study assessed resting energy expenditure (REE) in newborns with BPD.

METHODS

BPD was classified as mild and moderate/severe. REE was assessed using indirect calorimetry between the time points of the discontinuation of oxygen (O) (T1) and at term-equivalent age (T2) in preterm newborns with BPD.

RESULTS

The moderate group (10 newborns) presented with higher REE (kcal/kg/day) after discontinuation of mechanical ventilation and a decrease of 18% between the two time points; 72.7 and 59.6 kcal/kg/day at T1 and T2 respectively (p value 0.08). No differences were observed in REE in the mild BPD group between timepoints; 50.9-56.4 kcal/kg/day at T1 and T2 respectively (p value 0.73).

CONCLUSION

Newborns with BPD presented different metabolic behaviors depending on the classification criteria: those classified as having moderate BPD showed a decrease in REE toward term-equivalent age.

摘要

背景与目的

患有支气管肺发育不良（BPD）的新生儿报告的能量消耗更高。本研究评估了患有 BPD 的新生儿的静息能量消耗（REE）。

方法

将 BPD 分为轻度和中重度/重度。在患有 BPD 的早产儿中，在停止吸氧（O）的时间点（T1）和足月龄时（T2）之间使用间接热量法评估 REE。

结果

机械通气停止后，中度组（10 名新生儿）的 REE（千卡/千克/天）较高，两个时间点之间下降了 18%；分别为 72.7 和 59.6 kcal/kg/day（p 值为 0.08）。轻度 BPD 组在两个时间点之间，REE 无差异；分别为 50.9-56.4 kcal/kg/day（p 值为 0.73）。