Phillips McLeod, Bullock Garrett, Scott Aaron
Wake Forest University School of Medicine, Winston-Salem, NC, USA.
University of Oxford, Oxford, UK.
Foot Ankle Orthop. 2022 Sep 27;7(3):24730114221123804. doi: 10.1177/24730114221123804. eCollection 2022 Jul.
The hindfoot fusion nail has become a popular implant for tibiotalocalcaneal (TTC) arthrodeses given its rigidity, ease of insertion, and potential for less invasive surgical approaches. The purpose of this study was to evaluate fusion and complication rates following the use of a straight, retrograde intramedullary nail for TTC arthrodeses, and the influence of diabetes and smoking on these results.
A review of patient cases performed by a single surgeon at a single institution was performed. Variables included age, comorbidities, smoking history, BMI, hemoglobin A, preoperative and postoperative visual analog scale pain scores, assessment of healing, and complications. Relative and absolute risk were assessed for smoking, diabetes, fusion, and surgical complications through risk ratios. Cox proportional hazards survival analyses were performed to assess the effects of smoking and diabetes on fusion rates and complications. Linear regressions were performed to investigate the effects of smoking and diabetes on patient-reported pain levels.
Of 103 patients, there were 37 cigarette smokers and 30 diabetic patients. Eighty-three patients achieved union of all involved joints and 19 patients achieved union of 1 or 2 joints. Smokers demonstrated a 1.46 (risk ratio) (95% CI 1.03-2.07) times greater risk of nonunion but were not at an increased risk of experiencing surgical complications (0.86, 95% CI 0.56-1.33). Diabetic patients did not demonstrate an increased risk of nonunion (0.86, 95% CI 0.56-1.33) or complications (1.18, 95% CI 0.76-1.83).
Because of increased nonunion risk, patients undergoing elective tibiotalocalcaneal arthrodesis should be counseled increased nonunion risks associated with smoking. In this series, we did not find a relationship between diabetes and complications or nonunion.
Level III, retrospective cohort study.
由于其具有刚性、易于插入以及可采用潜在的微创手术入路等特点,后足融合钉已成为胫距跟(TTC)关节融合术常用的植入物。本研究的目的是评估使用直的逆行髓内钉进行TTC关节融合术后的融合率和并发症发生率,以及糖尿病和吸烟对这些结果的影响。
对单一机构的一位外科医生所做的患者病例进行回顾。变量包括年龄、合并症、吸烟史、体重指数、糖化血红蛋白、术前和术后视觉模拟评分疼痛评分、愈合评估以及并发症。通过风险比评估吸烟、糖尿病、融合及手术并发症的相对风险和绝对风险。进行Cox比例风险生存分析以评估吸烟和糖尿病对融合率及并发症的影响。进行线性回归以研究吸烟和糖尿病对患者报告的疼痛水平的影响。
103例患者中,有37例吸烟者和30例糖尿病患者。83例患者所有受累关节实现融合,19例患者1个或2个关节实现融合。吸烟者发生不愈合的风险比为1.46(95%可信区间1.03 - 2.07)倍,但发生手术并发症的风险并未增加(0.86,95%可信区间0.56 - 1.33)。糖尿病患者发生不愈合(0.86,95%可信区间0.56 - 1.33)或并发症(1.18,95%可信区间0.76 - 1.83)的风险并未增加。
由于不愈合风险增加,对于接受择期胫距跟关节融合术的患者,应告知其吸烟会增加不愈合风险。在本系列研究中,我们未发现糖尿病与并发症或不愈合之间存在关联。
III级,回顾性队列研究。