Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
Can Vet J. 2022 Oct;63(10):1051-1056.
Atrial fibrillation (AF) is the most clinically relevant cardiac arrhythmia identified in the Standardbred racehorse. However, there is limited literature regarding athletic ability in Standardbred racehorses following AF conversion. To investigate this issue, the objectives of this review were to: i) determine the success rate in using quinidine sulphate to treat AF in a population of hospitalized equine patients in Atlantic Canada between January 2008 and December 2019; and ii) measure return to athletic ability (using racetrack earnings and top-3 finishes) following cardioversion with quinidine sulphate in a population of Standardbred racehorses. Overall, 73% (16/22) of AF instances in this study were successfully treated with enteral quinidine sulphate. No significant difference was detected in racetrack earnings or number of top-3 finishes for each horse that raced at least 5 times pre- and post-conversion. Key clinical message: To the authors' knowledge, this is the first published review to assess the athletic ability of Standardbred racehorses following cardioversion with enteral quinidine sulphate. Based on the current information, it does not appear that treatment of AF with quinidine sulphate affects future athletic performance in horses that achieved cardioversion.
心房颤动(AF)是在标准赛马中发现的最具临床相关性的心律失常。然而,关于 AF 转为窦性心律后标准赛马的运动能力,相关文献有限。为了研究这个问题,本综述的目的是:i)确定 2008 年 1 月至 2019 年 12 月期间,在加拿大大西洋地区住院的马属动物中,使用硫酸奎尼丁治疗 AF 的成功率;ii)测量使用硫酸奎尼丁转复窦性心律后,标准赛马重返运动能力(使用赛道收入和前 3 名完赛成绩)的情况。总体而言,在这项研究中,73%(16/22)的 AF 病例经口服硫酸奎尼丁治疗成功。在转复前后至少 5 次参赛的每匹马的赛道收入或前 3 名完赛次数方面,没有发现显著差异。主要临床意义:据作者所知,这是第一篇评估使用口服硫酸奎尼丁转复窦性心律后标准赛马运动能力的已发表综述。根据目前的信息,硫酸奎尼丁治疗 AF 似乎不会影响转为窦性心律的马的未来运动表现。