Coss K C, Wheat L J, Conces D J, Brashear R E, Hull M T
Am J Med. 1987 Aug;83(2):343-6. doi: 10.1016/0002-9343(87)90709-1.
A 41-year-old man was admitted for evaluation of hemoptysis, dysphagia, and pleuritic chest pain associated with a mediastinal mass. Esophagography demonstrated a fistula between the mass and the esophagus. Results of histoplasmosis complement fixation serologic testing suggested an active infection. A methenamine silver stain of a lymph node obtained at mediastinoscopy revealed Histoplasmosis capsulatum. The patient was successfully treated with amphotericin B. This is believed to be the first reported case of an esophageal fistula as a complication of mediastinal histoplasmosis successfully treated with amphotericin B.
一名41岁男性因咯血、吞咽困难及与纵隔肿块相关的胸膜炎性胸痛入院评估。食管造影显示肿块与食管之间存在瘘管。组织胞浆菌补体结合血清学检测结果提示存在活动性感染。纵隔镜检查获取的淋巴结进行甲胺银染色显示荚膜组织胞浆菌。该患者接受两性霉素B治疗成功。据信这是首例报道的纵隔组织胞浆菌病并发食管瘘且经两性霉素B成功治疗的病例。