Kukliński Jakub, Steckiewicz Karol P, Owczuk Radosław
Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.
Wideochir Inne Tech Maloinwazyjne. 2022 Sep;17(3):457-466. doi: 10.5114/wiitm.2022.116750. Epub 2022 Jun 19.
INTRODUCTION: It is suggested that preoperative carbohydrate loading may have beneficial effects, which is emphasised in Enhanced Recovery After Surgery protocols (ERAS). Recent data confirmed that carbohydrate loading shortens length of hospital stay. AIM: In this systematic review we aimed to determine whether carbohydrate loading have positive effects in patients undergoing 1-day surgery. MATERIAL AND METHODS: We searched 5 databases and identified some randomized controlled trials which were reviewed independently by two reviewers. In the end 6 RCTs were included, involving 411 patients. Studies compared effects of carbohydrate loading vs. fasting and/or placebo on the following outcomes: thirst, hunger, postoperative nausea and vomiting (PONV), fatigue, pain and postoperative insulin resistance. In most cases data are inconclusive as studies reported opposite results. CONCLUSIONS: It seems that carbohydrate loading did not have a significant impact when compared to fasting or placebo. Preoperative carbohydrate loading seems not to have significant benefits over fasting or placebo in patients qualified for 1-day surgery.
引言:有人提出术前碳水化合物负荷可能具有有益作用,这在术后加速康复方案(ERAS)中得到了强调。最近的数据证实,碳水化合物负荷可缩短住院时间。 目的:在本系统评价中,我们旨在确定碳水化合物负荷对接受日间手术的患者是否有积极影响。 材料与方法:我们检索了5个数据库,并确定了一些随机对照试验,由两名评价者独立进行评价。最终纳入了6项随机对照试验,涉及411例患者。研究比较了碳水化合物负荷与禁食和/或安慰剂对以下结局的影响:口渴、饥饿、术后恶心呕吐(PONV)、疲劳、疼痛和术后胰岛素抵抗。在大多数情况下,由于研究报告了相反的结果,数据尚无定论。 结论:与禁食或安慰剂相比,碳水化合物负荷似乎没有显著影响。对于适合日间手术的患者,术前碳水化合物负荷似乎并不比禁食或安慰剂有显著益处。
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