Inagi Yoshihide, Kitagawa Atsushi, Miyaji Kagami, Takanashi Manabu, Honda Takashi, Okamura Toru, Hirata Yoichiro, Nakanishi Hidehiko, Ishikura Kenji
Department of Pediatrics, Kitasato University School of Medicine, Kanagawa, Japan.
Department of Cardiovascular Surgery, Kitasato University School of Medicine, Kanagawa, Japan.
J Cardiol Cases. 2022 Jun 24;26(4):283-285. doi: 10.1016/j.jccase.2022.05.014. eCollection 2022 Oct.
Ductus arteriosus aneurysm (DAA) is a rare cardiovascular anomaly, and thrombosis of DAA is even less common. The management of asymptomatic DAA with a thrombus is controversial. We here report a neonate with a thrombus from a DAA that grew rapidly into the pulmonary artery. The thrombus was detected incidentally in the main pulmonary artery by routine screening echocardiography. There was no clinical evidence of its presence until a few days after birth. The thrombus grew rapidly, despite administration of heparin. Six days after birth, the patient became cyanotic and had developed right ventricular pressure overload as a result of obstruction of the left pulmonary artery. The thrombus was immediately removed and the DAA resected. The patient was discharged home without any complications. Complications related to thrombus of a DAA can be critical and therefore require careful monitoring.
A thrombus extending from a ductus arteriosus aneurysm into the pulmonary artery can have serious consequences; thus, careful monitoring is required. Any signs of such complications should prompt immediate consideration of removal of the aneurysm and thrombus.
动脉导管瘤(DAA)是一种罕见的心血管异常,而动脉导管瘤血栓形成则更为少见。对于无症状的伴有血栓的动脉导管瘤的处理存在争议。我们在此报告一名患有动脉导管瘤血栓的新生儿,该血栓迅速生长至肺动脉。通过常规筛查超声心动图在主肺动脉中偶然发现了血栓。出生后数天内均无其存在的临床证据。尽管使用了肝素,血栓仍迅速生长。出生后6天,患者出现青紫,并因左肺动脉阻塞而出现右心室压力过载。立即取出血栓并切除动脉导管瘤。患者出院时无任何并发症。与动脉导管瘤血栓相关的并发症可能很严重,因此需要仔细监测。
从动脉导管瘤延伸至肺动脉的血栓可能会产生严重后果;因此,需要仔细监测。此类并发症的任何迹象都应促使立即考虑切除动脉瘤和血栓。