Zhou Suna, Meng Yinnan, Sun Xuefeng, Jin Zhicheng, Feng Wei, Yang Haihua
Key Laboratory of Radiation Oncology, The Affiliated Taizhou Hospital, Wenzhou Medical University, Taizhou, 317000, Zhejiang, PR China.
Department of Radiation Oncology, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, Shanxi, 710018, PR China.
Future Oncol. 2022 Oct;18(31):3551-3562. doi: 10.2217/fon-2022-0291. Epub 2022 Oct 3.
Adaptive radiotherapy (ART) is a new radiotherapy technology based on image-guided radiation therapy technology, used to avoid radiation overexposure to residual tumors and the surrounding normal tissues. Tumors undergoing the same radiation doses and modes can occur unequal shrinkage due to the variation of response times to radiation doses in different patients. To perform ART effectively, eligible patients with a high probability of benefits from ART need to be identified. Confirming the precise timetable for ART in every patient is another urgent problem to be resolved. Moreover, the outcomes of ART are different depending on the various image guidance used. This review discusses 'who, when and how' as the three key factors involved in the most effective implementation for the management of ART.
自适应放射治疗（ART）是一种基于图像引导放射治疗技术的新型放射治疗技术，用于避免对残留肿瘤和周围正常组织的辐射过度暴露。由于不同患者对辐射剂量的反应时间存在差异，接受相同辐射剂量和模式的肿瘤可能会出现不等的缩小。为了有效地实施ART，需要识别出有可能从ART中获益的合格患者。确定每位患者ART的确切时间表是另一个亟待解决的问题。此外，根据所使用的各种图像引导方式，ART的结果也有所不同。本综述讨论了“谁、何时以及如何”这三个关键因素，它们是ART管理最有效实施过程中所涉及的因素。
