比较青光眼疑似患者在蓝黄对比和绿黄对比视野检查中的视网膜敏感度。

Comparing retinal sensitivities on blue-on-yellow and green-on-yellow perimetry in glaucoma suspects.

机构信息

Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.

Department of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.

出版信息

Indian J Ophthalmol. 2022 Oct;70(10):3550-3555. doi: 10.4103/ijo.IJO_944_22.

DOI:10.4103/ijo.IJO_944_22

PMID:36190045

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9789795/

Abstract

PURPOSE

To compare the retinal sensitivities between the blue-on-yellow perimetry (BYP)/short-wavelength automated perimetry (SWAP) and green-on-yellow perimetry (GYP) among patients with and without nuclear sclerosis among glaucoma suspects.

METHODS

After ophthalmic examination, patients were subjected to two perimetric tests: BYP and GYP. The visual field (VF) parameters were compared between the two perimeters (p < 0.05 was considered significant).

RESULTS

Fifty-five eyes of 39 patients with a mean age of 60.53 ± 9.70 years were included in the study. Twenty-one eyes had clear lens or pseudophakia. Twenty-six eyes had lower grades of nuclear sclerosis (NO2NC2, NO3NC3) and eight eyes had higher grades of cataract (NO4NC4, NO5NC5). The mean retinal sensitivity (RS) in BYP was 22.08 ± 5.02 (dB) and in GYP was 23.84 ± 5.50 (dB) (p = 0.08). The mean defect in BYP was -2.56 ± 4.40 (dB) and in GYP was -3.24 ± 5.05 (dB), pattern standard deviation (PSD) in BYP was 3.65 ± 1.91 (dB) and in GYP was 3.83 ± 1.99 (dB), and foveal threshold (FT) was 24.20 ± 4.32 (dB) in BYP and 28.10 ± 4.50 (dB) in GYP. The two perimeters showed good agreement by the Bland-Altman plot for all parameters. Fourteen eyes showed perimetric changes suggestive of glaucoma by BYP. In these, GYP had a sensitivity of 92.86% (95% CI of 66.13% to 99.82%) and specificity of 95.12% (95% CI of 83.47% to 99.40%).

CONCLUSION

BYP and GYP show good agreement. They are comparable in clear media as well as in different grades of nuclear sclerosis. GYP showed good sensitivity and specificity compared to BYP.

摘要

目的

比较蓝/黄视野检查（BYP）/短波长自动化视野检查（SWAP）与绿/黄视野检查（GYP）在疑似青光眼患者中核硬化程度不同的患者之间的视网膜敏感度。

方法

眼科检查后，患者接受两种视野检查：BYP 和 GYP。比较两种视野检查的视野参数（p<0.05 为有统计学意义）。

结果

研究纳入了 39 名患者的 55 只眼，平均年龄为 60.53±9.70 岁。21 只眼晶状体透明或人工晶状体在位。26 只眼核硬化程度较低（NO2NC2、NO3NC3），8 只眼核硬化程度较高（NO4NC4、NO5NC5）。BYP 的平均视网膜敏感度（RS）为 22.08±5.02（dB），GYP 为 23.84±5.50（dB）（p=0.08）。BYP 的平均缺损值为-2.56±4.40（dB），GYP 为-3.24±5.05（dB），BYP 的模式标准差（PSD）为 3.65±1.91（dB），GYP 为 3.83±1.99（dB），BYP 的中央凹阈值（FT）为 24.20±4.32（dB），GYP 为 28.10±4.50（dB）。通过 Bland-Altman 图，两种视野检查在所有参数上均具有良好的一致性。BYP 检查发现 14 只眼有疑似青光眼的视野改变。在这些眼中，GYP 的敏感性为 92.86%（95%可信区间为 66.13%至 99.82%），特异性为 95.12%（95%可信区间为 83.47%至 99.40%）。