经皮肾镜取石术联合针状肾镜取石术对复杂性肾结石患者肾功能及并发症发生率的影响
Effect of Percutaneous Nephrolithotomy Combined with Needle Nephrolithotomy on Renal Function and Complication Rate in Patients with Complex Renal Calculi.
作者信息
Ge Guangcheng, Wang Chenghao
机构信息
Zhenjiang Hospital of Chinese Traditional and Western Medicine Urology Surgery, Zhenjiang 212000, China.
出版信息
Evid Based Complement Alternat Med. 2022 Sep 19;2022:7312960. doi: 10.1155/2022/7312960. eCollection 2022.
OBJECTIVE
To investigate the effect of percutaneous nephrolithotomy combined with needle nephrolithotomy on renal function and incidence of complications in patients with complex renal calculi.
METHODS
From March 2020 to March 2022, 88 patients with complex renal calculi were enrolled and divided into two groups. Percutaneous nephrolithotomy (PCNL) was performed in the control group, and percutaneous nephrolithotomy combined with needle nephrolithotomy was performed in the study group. Perioperative conditions, renal function parameters such as blood urea nitrogen (BUN), serum creatinine (Scr), and cystatin C (CysC) levels, inflammatory factors such as C-reactive protein (CRP) and procalcitonin (PCT) levels before surgery and 1 day after surgery were determined. The incidence of complications was statistically analyzed between two groups.
RESULTS
There was no significant difference in stone clearance rate between the two groups. The operation time and hospital stay in the study group were shorter than those in the control group. The intraoperative blood loss was less than that in the control group. The VAS score was lower than that in the control group. BUN, Scr, and CysC in the study group were not significantly different from those in the control group. CRP and PCT in the two groups at 1 d after surgery were higher than those before surgery, but CRP and PCT in the study group were lower than those in the control group. The incidence of complications in the study group was lower than that in the control group.
CONCLUSION
Percutaneous nephrolithotomy combined with needle nephrolithotomy is effective and safe in the treatment of complex renal calculi.
目的
探讨经皮肾镜取石术联合针状肾镜取石术对复杂性肾结石患者肾功能及并发症发生率的影响。
方法
选取2020年3月至2022年3月收治的88例复杂性肾结石患者，分为两组。对照组行单纯经皮肾镜取石术（PCNL），研究组行经皮肾镜取石术联合针状肾镜取石术。观察两组患者围手术期情况，测定术前及术后1天的肾功能指标如血尿素氮（BUN）、血清肌酐（Scr）、胱抑素C（CysC）水平，以及炎症因子如C反应蛋白（CRP）、降钙素原（PCT）水平。对两组并发症发生率进行统计学分析。
结果
两组结石清除率差异无统计学意义。研究组手术时间和住院时间均短于对照组，术中出血量少于对照组，视觉模拟评分（VAS）低于对照组。研究组BUN、Scr、CysC与对照组比较差异无统计学意义。两组术后1天CRP、PCT均高于术前，但研究组低于对照组。研究组并发症发生率低于对照组。
结论
经皮肾镜取石术联合针状肾镜取石术治疗复杂性肾结石安全有效。
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