Binder S, Sokal D, Maughan D
Arch Environ Health. 1986 Nov-Dec;41(6):341-5. doi: 10.1080/00039896.1986.9935776.
In this pilot study, we modified methods used in estimating the amount of soil ingested by ruminants to measure soil ingested by children. Using aluminum, silicon, and titanium as tracers, we estimated soil ingestion for 59 children aged 1-3 yr from East Helena, Montana. Estimated daily soil ingestion based on aluminum and silicon concentrations were 181 and 184 mg/day, respectively, whereas the estimate based on the titanium concentration was about 10 times higher, 1,834 mg/day. Although we do not consider these estimates accurate measures of soil ingestion, the method we used is a reasonable approach that, to our knowledge, has not been used before in humans. However, our estimates will be revised as refinement of this method and better understanding of the metabolism of aluminum, silicon, and titanium lead to more accurate data for analysis.
在这项初步研究中,我们修改了用于估算反刍动物摄入土壤量的方法,以测量儿童摄入的土壤量。我们使用铝、硅和钛作为示踪剂,估算了来自蒙大拿州东海伦娜的59名1至3岁儿童的土壤摄入量。基于铝和硅浓度估算的每日土壤摄入量分别为181毫克/天和184毫克/天,而基于钛浓度的估算值则高出约10倍,为1834毫克/天。尽管我们不认为这些估算值是土壤摄入量的准确测量,但据我们所知,我们使用的方法是一种合理的方法,此前尚未在人类中使用过。然而,随着该方法的完善以及对铝、硅和钛代谢的更好理解带来更准确的分析数据,我们的估算值将会得到修正。