Department of Thoracic Surgery, Tokyo Medical University Ibaraki Medical Center, Ami-machi, Ibaraki, Japan.
Department of Surgery, Tokyo Medical University, Tokyo, Japan.
Ann Thorac Cardiovasc Surg. 2024 Jan 26;30(1). doi: 10.5761/atcs.cr.22-00138. Epub 2022 Oct 5.
A 71-year-old man was diagnosed as having right primary lung squamous cell carcinoma, clinical stage IIIA, but he refused treatment. However, the right upper lobe nodule and lymph node (LN) #4R showed gradual shrinking without treatment. Four years after the diagnosis, a new nodule was detected in the left lung field. We considered that this new nodule might be metachronous primary lung cancer, and hence resected it for diagnosis and treatment. The tumor in the left lung was diagnosed as basaloid squamous cell carcinoma, and that in LN #4R was diagnosed as squamous cell carcinoma with keratinization. Therefore, the patient was diagnosed as having metachronous primary lung cancer that developed during the spontaneous regression of locally advanced lung cancer.
一位 71 岁男性被诊断为右肺原发性鳞状细胞癌，临床分期 IIIA，但他拒绝治疗。然而，右上肺结节和淋巴结（LN）#4R 在未经治疗的情况下逐渐缩小。诊断后四年，左肺野发现新结节。我们认为这个新结节可能是异时性原发性肺癌，因此将其切除进行诊断和治疗。左肺肿瘤被诊断为基底样鳞状细胞癌，LN#4R 的肿瘤被诊断为角化的鳞状细胞癌。因此，该患者被诊断为局部晚期肺癌自发消退过程中发生的异时性原发性肺癌。
