Molecular cloning and cDNA structure of the regulatory subunit of type I cAMP-dependent protein kinase from rat brain.
作者信息
Kuno T, Ono Y, Hirai M, Hashimoto S, Shuntoh H, Tanaka C
出版信息
Biochem Biophys Res Commun. 1987 Jul 31;146(2):878-83. doi: 10.1016/0006-291x(87)90612-7.
PMID:3619906
Abstract
Complementary DNA (cDNA) clones encoding the regulatory subunit of the type I cAMP-dependent protein kinase (R-I) were isolated by screening of rat brain cDNA libraries. A 1.5-kilobase (kb) cDNA insert containing the entire coding region was sequenced and full amino acid sequence has been deduced from the nucleotide sequence. The clone encodes for a protein of 380 amino acids that shows 97% homology to the bovine R-I subunit. Northern blot analysis demonstrated two major mRNA species (2.8 and 4.4 kb in size) in rat brain and liver.
摘要
相似文献
1
Molecular cloning and cDNA structure of the regulatory subunit of type I cAMP-dependent protein kinase from rat brain.
Biochem Biophys Res Commun. 1987 Jul 31;146(2):878-83. doi: 10.1016/0006-291x(87)90612-7.
2
3
Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis.
Biochem Biophys Res Commun. 1987 Dec 31;149(3):939-45. doi: 10.1016/0006-291x(87)90499-2.
4
The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.
Proc Natl Acad Sci U S A. 1987 Aug;84(15):5192-6. doi: 10.1073/pnas.84.15.5192.
5
6
Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3'-5'-cyclic adenosine monophosphate-dependent protein kinase from human testis.人睾丸中3'-5'-环磷酸腺苷依赖性蛋白激酶的激素诱导调节亚基的分子克隆、互补脱氧核糖核酸结构及预测的全长氨基酸序列
Mol Endocrinol. 1988 Dec;2(12):1364-73. doi: 10.1210/mend-2-12-1364.
7
Molecular cloning, cDNA structure and deduced amino acid sequence for the hormone-induced regulatory subunit (RII beta) of cAMP-dependent protein kinase from rat ovarian granulosa cells.
Biochem Biophys Res Commun. 1988 Jul 29;154(2):705-11. doi: 10.1016/0006-291x(88)90197-0.
8
Deduced primary structure of the beta subunit of brain type II Ca2+/calmodulin-dependent protein kinase determined by molecular cloning.通过分子克隆确定的脑II型钙/钙调蛋白依赖性蛋白激酶β亚基的推导一级结构。
Proc Natl Acad Sci U S A. 1987 Apr;84(7):1794-8. doi: 10.1073/pnas.84.7.1794.
9
Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases.
Biochem Biophys Res Commun. 1991 Apr 15;176(1):166-72. doi: 10.1016/0006-291x(91)90904-l.
10
Isolation of a cDNA and characterization of the 5' flanking region of the gene encoding the type I regulatory subunit of the cAMP-dependent protein kinase.
Eur J Biochem. 1987 Aug 17;167(1):27-33. doi: 10.1111/j.1432-1033.1987.tb13300.x.
Zotero 插件