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下颌骨双侧巨大复杂复合性牙瘤:一例罕见病例报告

Bilateral Massive Complex Composite Odontoma of the Mandible: A Rare Case Report.

作者信息

Singh Priyankar, Iqbal Jawed, Imam Zeenat S, Biswas Krishna P, Singh Nimmi, Mishra Navin

机构信息

Department of Cranio-Maxillo-Facial Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.

Department of Dentistry, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.

出版信息

Ann Maxillofac Surg. 2022 Jan-Jun;12(1):87-90. doi: 10.4103/ams.ams_245_21. Epub 2022 May 4.

Abstract

RATIONALE

Odontomas result from abnormal growth of differentiated epithelial and mesenchymal cells, which form ameloblasts and odontoblasts along with pulp tissue at times.

PATIENT CONCERNS

A patient reported with a chief complaint of hard swelling of the lower jaw causing difficulty in mouth opening and facial deformity.

DIAGNOSIS

A provisional diagnosis of complex odontome based on clinicoradiological findings was made, which was later confirmed as complex composite odontome histologically.

TREATMENT

Bilateral hard tissue mass was surgically removed from the mandible with utmost precaution to prevent jaw deformity. On fine separation, the specimen yielded nearly 82 small teeth-like structures.

OUTCOMES

Histopathologically, multiple small teeth-like structures with haphazardly arranged central fibrofatty pulpal stroma surrounded by well-formed dentinal tubules and empty areas representing decalcified enamel matrix surrounded by fibrovascular stroma at the periphery were seen.

TAKE-AWAY LESSONS: Early diagnosis and treatment ensures minimal surrounding deformities, better prognosis, and less chances of recurrence.

摘要

理论依据

牙瘤由分化的上皮细胞和间充质细胞异常生长形成,这些细胞有时会连同牙髓组织一起形成成釉细胞和成牙本质细胞。

患者关注点

一名患者主诉下颌硬肿,导致张口困难和面部畸形。

诊断

根据临床影像学检查结果初步诊断为复合性牙瘤,后经组织学确诊为复合性混合性牙瘤。

治疗

极其小心地从下颌骨手术切除双侧硬组织肿块,以防止颌骨畸形。精细分离后,标本产生了近82个小牙齿样结构。

结果

组织病理学检查可见多个小牙齿样结构,中央纤维脂肪性牙髓基质排列杂乱,周围有形成良好的牙本质小管,周边纤维血管基质围绕着代表脱钙釉质基质的空白区域。

经验教训

早期诊断和治疗可确保周围畸形最小、预后更好且复发几率更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c598/9527836/88c8d48db7af/AMS-12-87-g001.jpg

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