DeWitt J R, D'Andrea J A, Emmerson R Y, Gandhi O P
Bioelectromagnetics. 1987;8(2):149-57. doi: 10.1002/bem.2250080205.
Adult male, Long-Evans rats were exposed 7 h a day for 90 days to continuous wave (CW) 2,450-MHz microwaves at an average power density of 0.5 mW/cm2. Exposures were in a monopole-above-ground radiation chamber with rats in Plexiglas cages. The resulting specific absorption rate (SAR) was 0.14 W/kg (+/- 0.01 SEM). Additional rats served as sham-exposed and home-caged controls. All were evaluated daily for body mass and food and water intakes. Once each 30 days, throughout baseline and exposure phases of the experiment, rats in the sham- and microwave-exposed groups were tested for their sensitivity to footshock. After 90-days of exposure, the rats were evaluated an open field, an active avoidance task and an operant task for food reinforcement. Performance of sham- and microwave-irradiated rats was reliably different on only one measure, the lever-pressing task. The general conclusion reached was that exposure to CW 2,450-MHz microwave radiation at 0.5 mW/cm2 was below the threshold for behavioral effects over a wide range of variables, but did have an effect on a time-related operant task, although the direction of the effect was unpredictable.
成年雄性Long-Evans大鼠每天暴露于平均功率密度为0.5 mW/cm²的2450 MHz连续波(CW)微波下7小时,持续90天。暴露是在一个地面上方的单极辐射室中进行的,大鼠置于有机玻璃笼中。由此产生的比吸收率(SAR)为0.14 W/kg(±0.01标准误)。另外的大鼠作为假暴露和笼养对照。每天对所有大鼠的体重、食物和水摄入量进行评估。在整个实验的基线期和暴露期,每隔30天对假暴露组和微波暴露组的大鼠进行足部电击敏感性测试。暴露90天后,对大鼠进行旷场试验、主动回避任务和食物强化操作性任务评估。假暴露组和微波照射组大鼠的表现仅在一项指标(杠杆按压任务)上存在显著差异。得出的总体结论是,暴露于0.5 mW/cm²的2450 MHz连续波微波辐射下,在广泛的变量范围内低于行为效应阈值,但确实对一项与时间相关的操作性任务有影响,尽管影响的方向不可预测。