Lakshmanan Archana, Parameswaran Ashok
Department of Histopathology, Apollo Hospitals, Chennai, India.
Department of Pathology, Apollo Hospitals, Chennai, India.
J Orthop Case Rep. 2022 Feb;12(2):61-64. doi: 10.13107/jocr.2022.v12.i02.2668.
Fibrocartilaginous dysplasia (FCD) is a variant of fibrous dysplasia (FD) with extensive cartilaginous differentiation. This has been reported in both monostotic and polyostotic types of FD, the proximal femur being the most common site involved.
We report five cases of fibrocartilaginous dysplasia with varying degrees of cartilaginous differentiation. The age of the patients ranged from 7 to 30 years, and there was a female predominance (M:F ratio of 1:4). The proximal femur was the site of involvement in all the cases. Imaging showed well demarcated radiolucent lesions with stippled calcifications. Histologically, cartilaginous areas were noted juxtaposed to typical areas of fibrous dysplasia. Four of the patients were treated with curettage and one with a marginal resection. None of the five cases had recurrences at the past follow-up.
FCD is a rare variant of fibrous dysplasia which needs to diagnosed and treated early, as there is a high risk of pathological fracture.
纤维软骨发育异常（FCD）是纤维发育异常（FD）的一种变体，具有广泛的软骨分化。在单发性和多发性FD中均有报道，股骨近端是最常受累的部位。
我们报告了5例具有不同程度软骨分化的纤维软骨发育异常病例。患者年龄在7至30岁之间，女性占优势（男女比例为1:4）。所有病例均累及股骨近端。影像学显示边界清晰的透光性病变，伴有点状钙化。组织学上，软骨区域与纤维发育异常的典型区域相邻。4例患者接受了刮除术治疗，1例接受了边缘切除术。在过去的随访中，这5例患者均未复发。
FCD是纤维发育异常的一种罕见变体，由于存在病理性骨折的高风险，需要早期诊断和治疗。
