Kilinc Ayse Nur Ugur, Bayramoglu Zeynep, Unlu Yasar
Department of Pathology, Konya Training and Research Hospital, Konya, Turkiye.
North Clin Istanb. 2022 Jul 8;9(3):261-265. doi: 10.14744/nci.2020.78872. eCollection 2022.
Although basal cell carcinoma (BCC) is prevalent in the older population, it can be rarely seen in younger people. This study aims to investigate the risk factors and characteristics of BCC in young patients.
Pathology reports in a single tertiary care institution between 2010 and 2020 were retrospectively reviewed. Patients under the age of 35 who were diagnosed with BCC were included for the analysis. Data were gathered from medical records and pathology reports. Demographic characteristics, accompanying pathologies, and clinical findings of these patients were analyzed.
There were a total of 32 patients in our cohort. Out of 32 patients, 20 were female and 12 were male. One male patient and five female patients were younger than 18. An accompanying risk factor (Gorlin syndrome, XP, renal transplantation, etc.) was present in six patients. There were no known additional diseases or risk factors in 26 patients. Metastasis and recurrence were not reported in any of our patients. Contrary to the information in the literature, the patients with BCC at a young age were not found more aggressive in our study.
Contrary to the information in the literature, the patients with BCC at a young age were not found more aggressive in our study. Understanding the risk factors associated with BCC is essential for designing prevention strategies and favoring early diagnosis. Awareness of early-onset BCC aids in early diagnosis and treatment of the disease. Therefore, BCC should be in the differential diagnosis of skin lesions in the young population. In addition, when we encounter early-onset BCC, we should not forget the accompanying risk factors and syndromes.
尽管基底细胞癌(BCC)在老年人群中很常见,但在年轻人中却很少见。本研究旨在调查年轻患者BCC的危险因素和特征。
回顾性分析2010年至2020年期间一家三级医疗机构的病理报告。纳入35岁以下被诊断为BCC的患者进行分析。数据从病历和病理报告中收集。分析这些患者的人口统计学特征、伴随病变和临床发现。
我们的队列中共有32例患者。32例患者中,20例为女性,12例为男性。1例男性患者和5例女性患者年龄小于18岁。6例患者存在伴随危险因素(戈林综合征、着色性干皮病、肾移植等)。26例患者无已知的其他疾病或危险因素。我们的患者中均未报告转移和复发情况。与文献中的信息相反,在我们的研究中未发现年轻BCC患者更具侵袭性。
与文献中的信息相反,在我们的研究中未发现年轻BCC患者更具侵袭性。了解与BCC相关的危险因素对于设计预防策略和促进早期诊断至关重要。认识早发性BCC有助于疾病的早期诊断和治疗。因此,BCC应纳入年轻人群皮肤病变的鉴别诊断中。此外,当我们遇到早发性BCC时,不应忘记其伴随的危险因素和综合征。