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福尼尔坏疽的回顾性病例系列研究:及其阴茎覆盖的急诊处理与植皮技术

A Retrospective Case Series in Fournier's Disease: And Its Emergency Management et Grafting Technique for Penis Coverage.

作者信息

Tripodi Domenico, Guastafierro Antonio, Gagliardi Federica, Amabile Maria Ida, Lori Eleonora, Cirocchi Roberto, Pironi Daniele, Forte Flavio, Cannistra Claudio, Sorrenti Salvatore

机构信息

Department of Surgical Sciences, "Sapienza" University of Rome, Rome 00161, Italy.

Plastic and Reconstructive Surgery Unit, Centre Hospitalier Universitaire Bichat Claude-Bernard, Paris, France.

出版信息

Emerg Med Int. 2022 Sep 25;2022:6710777. doi: 10.1155/2022/6710777. eCollection 2022.

DOI:10.1155/2022/6710777
PMID:36200075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9527405/
Abstract

Fournier's gangrene is a necrotizing soft tissue infection of the genital, perineal, and perirectal areas. A primary isolated involvement of the penis is rare, but it can be affected in some circumstances. The purpose of this case series is to present the findings of our thirteen years' experience in the reconstruction of the penis in Fournier's gangrene and our full-thickness grafting technique to cover the penis rod. We retrospectively reviewed patient data who underwent a penis reconstruction following Fournier's gangrene in 2018. The data was analyzed to report the estimated percentage of complications, of patients with primary or secondary gangrene of the penis, the number of reinterventions, and finally the percentage of deaths or recovery. 23 patients underwent reconstruction with our technique of full-thickness skin graft. In all cases, the skin graft was harvested from the upper arm with an arrow shape mark. No further penile revision surgery was required, and neither patient complained about retraction, nor traction, or pain during erection. The donor site healed without any complications. We believe that the coverage of the penis using our grafting technique is safe, easily reproducible, and demonstrates excellent esthetic and functional results.

摘要

福尼尔坏疽是一种发生于生殖器、会阴和直肠周围区域的坏死性软组织感染。阴茎原发性孤立受累较为罕见,但在某些情况下也可能受到影响。本病例系列的目的是展示我们在福尼尔坏疽阴茎重建方面十三年的经验结果以及我们用于覆盖阴茎体的全厚皮片移植技术。我们回顾性分析了2018年因福尼尔坏疽接受阴茎重建的患者数据。对这些数据进行分析,以报告并发症的估计发生率、阴茎原发性或继发性坏疽患者的情况、再次干预的次数,以及最终的死亡或康复百分比。23例患者采用我们的全厚皮片技术进行了重建。在所有病例中,皮片均取自上臂,带有箭形标记。无需进一步的阴茎修复手术,且患者均未抱怨勃起时出现回缩、牵拉或疼痛。供区愈合良好,无任何并发症。我们认为,使用我们的移植技术覆盖阴茎是安全的,易于重复操作,并且具有出色的美学和功能效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/955b95d8dea4/EMI2022-6710777.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/43f7a36fa600/EMI2022-6710777.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/fe17ff1e9ef9/EMI2022-6710777.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/35ac33606c10/EMI2022-6710777.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/577bbc8de6e9/EMI2022-6710777.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/955b95d8dea4/EMI2022-6710777.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/43f7a36fa600/EMI2022-6710777.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/fe17ff1e9ef9/EMI2022-6710777.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/35ac33606c10/EMI2022-6710777.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/577bbc8de6e9/EMI2022-6710777.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2211/9527405/955b95d8dea4/EMI2022-6710777.005.jpg

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本文引用的文献

1
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2
Fatal infections in andrology. Atypical clinical presentation of a Fournier's disease.男科致命感染。坏疽性脓皮病的非典型临床表现。
Arch Ital Urol Androl. 2020 Oct 2;92(3). doi: 10.4081/aiua.2020.3.213.
3
Fournier's gangrene: a review of reconstructive options.福尼尔坏疽:重建治疗方案综述
Cent European J Urol. 2020;73(1):74-79. doi: 10.5173/ceju.2020.0060. Epub 2019 Dec 31.
4
Fournier's Gangrene and Intravenous Drug Abuse: an Unusual Case Report and Review of The Literature.福尼尔坏疽与静脉药物滥用:一例罕见病例报告及文献综述
Open Med (Wars). 2019 Dec 24;14:694-710. doi: 10.1515/med-2019-0114. eCollection 2019.
5
A curious case of Fournier's gangrene.一例罕见的福尼尔坏疽病例。
Urol Case Rep. 2019 Sep 4;27:101001. doi: 10.1016/j.eucr.2019.101001. eCollection 2019 Nov.
6
Skin Grafting Applications in Urology.皮肤移植在泌尿外科中的应用
Rev Urol. 2019;21(1):8-14.
7
A fatal case of Fournier's gangrene during neoadjuvant radiotherapy for rectal cancer.直肠癌新辅助放疗期间发生的致命性 Fournier 坏疽病例。
Strahlenther Onkol. 2019 May;195(5):441-446. doi: 10.1007/s00066-018-1401-4. Epub 2018 Nov 23.
8
Surgical management of buried penis in adults.成人隐匿阴茎的手术治疗
Cent European J Urol. 2018;71(3):346-352. doi: 10.5173/ceju.2018.1676. Epub 2018 Sep 22.
9
Fatal Fournier's gangrene caused by Clostridium ramosum in a patient with central diabetes insipidus and insulin-dependent diabetes mellitus: a case report.中枢性尿崩症合并胰岛素依赖型糖尿病患者由脆弱拟杆菌引起的致命性 Fournier 坏疽:病例报告。
BMC Infect Dis. 2018 Aug 2;18(1):363. doi: 10.1186/s12879-018-3280-9.
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Isolated Involvement of Penis in Fournier's Gangrene: A Rare Possibility.阴茎孤立性受累于福尼尔坏疽:一种罕见的可能性。
J Coll Physicians Surg Pak. 2018 Feb;28(2):164-165. doi: 10.29271/jcpsp.2018.02.164.