Giovannetti Olivia, Tomalty Diane, Velikonja Leah, Jurkus Connor, Adams Michael A
Department of Biomedical and Molecular Science, Queen's University, Kingston, Canada.
Clin Anat. 2023 Jan;36(1):118-127. doi: 10.1002/ca.23960. Epub 2022 Oct 17.
Detailed knowledge regarding the innervation and histology of the human cervix is crucial given the surgical removal of this tissue for conditions such as cervical dysplasia. Recent evidence implicates the cervix in the sexual response, making it pertinent to characterize this region to elucidate its role. Despite this, literature describing the overall innervation of the cervix from anatomical and histological perspectives is lacking. The aim of this review was to consolidate descriptions pertaining to human cervix innervation and discuss possible mechanisms of dysfunction, as an unintended result of cervix removal. A detailed literature search of relevant articles describing human cervix innervation was conducted. 1597 articles were screened based on the keywords searched. Only 16 articles, containing information regarding specific evidence of the innervation of the human cervix, were included and categorized based on parameters of innervation (method, type, location). The published evidence demonstrates that the human cervix has sympathetic, parasympathetic, and sensory innervation, but does not characterize changes after surgical procedures. Despite the gaps in knowledge, it is relevant that associations linking clinical procedures, involving cervical removal and adverse sexual health outcomes, become an important focus for discussions between physicians and patients. Future work is needed to better detail the affected innervation as well as the neural pathway-specific relationship to symptoms of sexual dysfunction.
鉴于因宫颈发育异常等情况需对该组织进行手术切除，了解人类宫颈的神经支配和组织学的详细知识至关重要。最近的证据表明宫颈参与性反应，因此有必要对该区域进行特征描述以阐明其作用。尽管如此，从解剖学和组织学角度描述宫颈整体神经支配的文献却很匮乏。本综述的目的是汇总有关人类宫颈神经支配的描述，并讨论因宫颈切除意外导致的功能障碍的可能机制。我们对描述人类宫颈神经支配的相关文章进行了详细的文献检索。根据搜索关键词筛选出1597篇文章。仅纳入了16篇包含人类宫颈神经支配具体证据信息的文章，并根据神经支配参数（方法、类型、位置）进行分类。已发表的证据表明，人类宫颈具有交感神经、副交感神经和感觉神经支配，但未描述手术操作后的变化。尽管存在知识空白，但将涉及宫颈切除的临床程序与不良性健康结果联系起来的关联，成为医生与患者之间讨论的重要焦点是很有意义的。未来需要开展更多工作，以更详细地了解受影响的神经支配以及神经通路与性功能障碍症状的特定关系。
