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老年急性非A型主动脉夹层:手术与内科治疗的比较。

Noncommunicating acute type A aortic dissection in elderly patients: Surgery versus medical management.

机构信息

Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, Kumamoto, Japan.

出版信息

Eur J Cardiothorac Surg. 2022 Nov 3;62(6). doi: 10.1093/ejcts/ezac484.

Abstract

OBJECTIVES

Our goal was to evaluate the surgical and conservative outcomes of acute type A aortic dissection with a thrombosed false lumen of the ascending aorta in elderly patients.

METHODS

Patients older than 75 years with acute type A aortic dissection admitted to our hospital from October 2011 to December 2020 were reviewed retrospectively, including those with the noncommunicating type without malperfusion and low physical capacity prehospitalization.

RESULTS

Sixty-six patients were enrolled consecutively in the medical (M, n = 30) and surgical (S, n = 36) groups. The ascending aorta was the most replaced section in the S group (78%). Groups did not differ significantly in hospital deaths and in intensive care unit and hospital stays. Two patients (7%) underwent surgery and 3 (10%) underwent redissection in the M group. No significant difference existed between the groups in the decline of physical performance during hospitalization. Seven patients in the M group (24%) had aorta-related events in the late period as opposed to none in the S group (P=0.003). Survival rates after 4 years were 78.3% and 71.4% in the S and M groups, respectively (P=0.154). The cumulative incidence of overall reintervention due to an aortic event was significantly higher in the M group; however, the 2 groups did not differ significantly in overall aorta-related deaths.

CONCLUSIONS

Surgical outcomes of noncommunicating acute type A aortic dissection in elderly patients were favorable. There was no significant difference in maintaining physical function at discharge, and the medical group had a significantly higher overall aortic event rate than the surgical group.

摘要

目的

评估老年急性 A 型主动脉夹层伴升主动脉血栓性假腔患者的手术和保守治疗结果。

方法

回顾性分析 2011 年 10 月至 2020 年 12 月我院收治的年龄大于 75 岁的急性 A 型主动脉夹层患者,包括非交通型无灌注不良且院前体力较差的患者。

结果

连续纳入 66 例患者,分别进入内科(M 组,n=30)和外科(S 组,n=36)组。S 组升主动脉置换比例最高(78%)。两组在院内死亡率、重症监护病房和住院时间方面无显著差异。M 组有 2 例(7%)患者行手术治疗,3 例(10%)患者行再夹层。M 组患者在住院期间体力下降程度无显著差异。M 组有 7 例(24%)患者在后期发生与主动脉相关的事件,而 S 组无患者发生(P=0.003)。S 和 M 组患者 4 年后的生存率分别为 78.3%和 71.4%(P=0.154)。M 组因主动脉事件再次干预的累积发生率明显更高,但两组主动脉相关死亡率无显著差异。

结论

老年非交通性急性 A 型主动脉夹层患者的手术治疗效果良好。两组患者出院时的体力功能保持情况无显著差异,且内科组的总体主动脉事件发生率明显高于外科组。

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