Hori Hitomi, Kaneko Shinji, Fujita Masaya, Nagai Shin, Ito Ryota, Shirai Yoshinori, Adachi Kentaro, Suzuki Noriyuki, Suzuki Junya, Kondo Kiyota, Yamauchi Ryota, Haga Tomoaki, Tatami Yosuke, Ohashi Taiki, Kubota Ryuji, Shinoda Masanori, Tanaka Akihito, Inden Yasuya, Murohara Toyoaki
Department of Cardiology, Toyota Kosei Hospital, 500-1 Ibohara, Josui-cho, Toyota, Japan.
Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
J Interv Card Electrophysiol. 2023 Apr;66(3):673-681. doi: 10.1007/s10840-022-01382-y. Epub 2022 Oct 6.
Mitral isthmus (MI) ablation for mitral flutter is technically difficult, and incomplete block line is not uncommon. The objective of this study is to investigate the effect of the ridge line of left pulmonary vein isolation (LPVI) from left atrial appendage (LAA) on completion rate of mitral isthmus (MI) block line and recurrence rate of atrial tachycardia (AT) or atrial flutter (AFL) after the first MI ablation.
We identified 611 patients who underwent first MI ablation for mitral flutter during the study period. Finally, 559 patients were enrolled and divided into two groups according to the method of ridge line ablation of LPVI (LAA group, n = 467, conventional group, n = 92). Outcome measures were the completion of MI block line by first MI ablation, the recurrence of AT/AFL, and repeat MI ablation after the first MI ablation.
The first MI block line completion rate was significantly higher in the LAA group than the conventional group (95% vs. 85%, p < 0.001). The recurrence rate of AT/AFL after 3 months from first MI ablation was significantly lower in the LAA group. The requirement of additional MI ablation tended to be lower in the LAA group.
Our novel approach of ablating LPV-LAA ridge from the LAA side during PVI can increase the success rate of MI block line completion, and reduce the recurrence rate of AT/AFL and the need for additional MI block line ablation. Graphical abstract Ablation of the left pulmonary vein-left atrial appendage ridge from the left atrial appendage side during PVI increased the success rate of mitral isthmus block line completion.
二尖瓣峡部(MI)消融治疗二尖瓣扑动技术难度大,阻滞线不完全常见。本研究的目的是探讨从左心耳(LAA)隔离左肺静脉(LPVI)的嵴线对首次MI消融后二尖瓣峡部(MI)阻滞线完成率及房性心动过速(AT)或心房扑动(AFL)复发率的影响。
我们确定了在研究期间接受首次MI消融治疗二尖瓣扑动的611例患者。最后,559例患者入组,并根据LPVI嵴线消融方法分为两组(LAA组,n = 467,传统组,n = 92)。观察指标为首次MI消融时MI阻滞线的完成情况、AT/AFL的复发情况以及首次MI消融后再次进行MI消融的情况。
LAA组首次MI阻滞线完成率显著高于传统组(95%对85%,p < 0.001)。首次MI消融后3个月时,LAA组AT/AFL的复发率显著更低。LAA组额外进行MI消融的需求倾向于更低。
我们在肺静脉隔离(PVI)期间从LAA侧消融LPV-LAA嵴的新方法可提高MI阻滞线完成成功率,降低AT/AFL复发率及额外MI阻滞线消融的需求。图形摘要:在PVI期间从左心耳侧消融左肺静脉-左心耳嵴提高了二尖瓣峡部阻滞线完成成功率。