Trapp T K, Fu Y S, Calcaterra T C
Arch Otolaryngol Head Neck Surg. 1987 Oct;113(10):1086-9. doi: 10.1001/archotol.1987.01860100064023.
Melanoma involving the nasal and paranasal sinus mucosa is a rare disease that is difficult to treat and generally has a poor prognosis. Data on 17 patients treated at the UCLA Medical Center during the period 1970 to 1985 were reviewed in a retrospective manner. The five-year disease-free survival was 25% (3/12). Surgery, with or without radiation therapy, is the mode of treatment to control disease in most patients. Treatment failures, which include both local recurrence and distant metastases, may occur many years after initial therapy. We found a correlation between the thickness of tumor and the clinical outcome.
累及鼻腔和鼻窦黏膜的黑色素瘤是一种罕见疾病，难以治疗，且总体预后较差。对1970年至1985年期间在加州大学洛杉矶分校医学中心接受治疗的17例患者的数据进行了回顾性分析。五年无病生存率为25%（3/12）。手术，无论是否联合放疗，是大多数患者控制疾病的治疗方式。治疗失败包括局部复发和远处转移，可能在初始治疗多年后发生。我们发现肿瘤厚度与临床结果之间存在相关性。
