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妊娠期糖尿病研究组印度分会(DIPSI)与世界卫生组织(1999)的 GDM 诊断标准:一项荟萃分析。

Diabetes in Pregnancy Study Group India (DIPSI) and WHO (1999) diagnostic criteria for GDM: A meta-analysis.

机构信息

Clinical Epidemiology Unit, All India Institute of Medical Sciences, New Delhi, India.

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Diabetes Metab Syndr. 2022 Oct;16(10):102622. doi: 10.1016/j.dsx.2022.102622. Epub 2022 Sep 23.

Abstract

BACKGROUND AND AIMS

The diagnosis of Gestational diabetes mellitus (GDM) is challenging and controversial due to the heterogeneity or lack of consensus regarding the screening and diagnostic criteria for GDM.

METHODS

A meta-analysis of studies comparing Diabetes in Pregnancy Study Group India (DIPSI) and WHO 1999 for diagnosing GDM was carried out.

RESULTS

A total of 6 comparative studies were included. Pooled analysis showed sensitivity and specificity as 0.79 (95% CI: 0.53 to 0.92) and 0.97 (95% CI: 0.94 to 0.98) respectively.

CONCLUSION

Based on the results of the meta-analysis, DIPSI showed higher specificity when compared to WHO 1999, hence may be used to rule in disease in probable GDM cases. However, the results should be interpreted more cautiously and carefully since only a few studies were included.

摘要

背景和目的

由于针对 GDM 的筛查和诊断标准存在异质性或缺乏共识,因此妊娠糖尿病(GDM)的诊断颇具挑战且颇具争议。

方法

对比较 Diabetes in Pregnancy Study Group India(DIPSI)和 WHO 1999 用于诊断 GDM 的研究进行了荟萃分析。

结果

共纳入 6 项比较研究。汇总分析显示,其灵敏度和特异性分别为 0.79(95%CI:0.53 至 0.92)和 0.97(95%CI:0.94 至 0.98)。

结论

基于荟萃分析的结果,DIPSI 与 WHO 1999 相比特异性更高,因此可能用于在疑似 GDM 病例中确诊疾病。但是,由于仅纳入了少数研究,因此应更谨慎和仔细地解释结果。

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